Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 10/20 | 0.44 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.41 |
| ▸ | CCNA2 | P20248 | 4/20 | 0.40 |
| ▸ | CDK2 | P24941 | 4/20 | 0.40 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.40 |
| ▸ | CDK1 | P06493 | 2/20 | 0.40 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.40 |
| ▸ | CDK7 | P50613 | 2/20 | 0.40 |
| ▸ | CDK9 | P50750 | 2/20 | 0.40 |
| ▸ | CCNH | P51946 | 2/20 | 0.40 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.39 |
| ▸ | CCNA1 | P78396 | 3/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | DYRK2 | Q92630 | 2/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31333857 | 0.92 | SYK (0.43) | SYKCHEK1CCNA2CDK2CCNT1 | |
| SCHEMBL31334964 | 0.90 | SYK (0.47) | SYKCHEK1CCNA2CDK2CCNT1 | |
| SCHEMBL31334756 | 0.90 | SYK (0.47) | SYKCHEK1CCNA2CDK2CCNT1 | |
| SCHEMBL31334535 | 0.90 | IRAK1 (0.45) | SYKCCNA2CDK2CCNT1CDK1 | |
| SCHEMBL31333422 | 0.87 | MAPK3 (0.44) | SYKCCNA2CDK2CCNT1CDK7 | |
| SCHEMBL31333461 | 0.86 | SYK (0.48) | SYKCCNA2CDK2CDK7MAPK3 | |
| SCHEMBL31335015 | 0.86 | SYK (0.44) | SYKCCNA2CDK2CCNT1CDK1 | |
| SCHEMBL31334114 | 0.85 | MAP4K1 (0.42) | SYKCCNA2CDK2MAPK3JAK2 | |
| SCHEMBL31334771 | 0.84 | SYK (0.42) | SYKCDK2CCNT1CDK1CCNB1 | |
| SCHEMBL31333243 | 0.84 | SYK (0.46) | SYKCCNA2CDK2CCNT1CDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709720-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | Larkspur Biosciences, Inc. (US) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233846-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | LARKSPUR BIOSCIENCES, INC. (US) | 2024-11-14 | — | — | WO | disclosed |