SCHEMBL31334423

SCHEMBL31334423

CC(C)(C)OC(=O)NC[C@H]1CC[C@H](N2CCC(c3ccc4c(c3)oc(=O)n4C3CCC(=O)NC3=O)CC2)CC1

nearest known ligand 0.41

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
DDB1 Q16531 8/20 0.41
CRBN Q96SW2 8/20 0.41
IKZF2 Q9UKS7 1/20 0.41
ASAH1 Q13510 9/20 0.39
FAAH O00519 1/20 0.39
NAAA Q02083 1/20 0.39
DRD2 P14416 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31334477 0.87 CRBN (0.41) DDB1CRBNDRD2
SCHEMBL31333843 0.86 DDB1 (0.50) DDB1CRBNIKZF2
SCHEMBL31333377 0.84 IKZF2 (0.40) DDB1CRBNIKZF2ASAH1FAAH
SCHEMBL31334664 0.83 DRD2 (0.44) DDB1CRBNIKZF2ASAH1FAAH
SCHEMBL31335114 0.83 IKZF2 (0.44) DDB1CRBNIKZF2ASAH1FAAH
SCHEMBL23540560 0.82 DDB1 (0.41) DDB1CRBNIKZF2ASAH1FAAH
SCHEMBL23541035 0.82 DDB1 (0.54) DDB1CRBNASAH1FAAHNAAA
SCHEMBL31334711 0.81 IKZF2 (0.45) DDB1CRBNIKZF2ASAH1FAAH
SCHEMBL23540692 0.79 DDB1 (0.51) DDB1CRBNDRD2
SCHEMBL31333308 0.79 DDB1 (0.48) DDB1CRBNIKZF2ASAH1FAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4709720-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN Larkspur Biosciences, Inc. (US) 2026-03-18 EP disclosed
WO-2024233846-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN LARKSPUR BIOSCIENCES, INC. (US) 2024-11-14 WO disclosed