Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | CKS1B | P61024 | 1/20 | 0.44 |
| ▸ | SKP1 | P63208 | 1/20 | 0.44 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.40 |
| ▸ | SYK | P43405 | 2/20 | 0.40 |
| ▸ | DYRK2 | Q92630 | 2/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.38 |
| ▸ | HRH1 | P35367 | 2/20 | 0.38 |
| ▸ | HTR2B | P41595 | 2/20 | 0.38 |
| ▸ | BTK | Q06187 | 1/20 | 0.38 |
| ▸ | CDK4 | P11802 | 2/20 | 0.38 |
| ▸ | CCND1 | P24385 | 2/20 | 0.38 |
| ▸ | CCND3 | P30281 | 2/20 | 0.38 |
| ▸ | CDK6 | Q00534 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31333206 | 0.90 | CKS1B (0.51) | MAPK1CKS1BSKP1SKP2KDM1A | |
| SCHEMBL31334005 | 0.89 | MAPK1 (0.47) | MAPK1MCHR1DYRK2CDK4CCND1 | |
| SCHEMBL31333816 | 0.88 | MAPK1 (0.47) | MAPK1CKS1BSKP1SKP2KDM1A | |
| SCHEMBL31334783 | 0.87 | MAPK8 (0.45) | MAPK1CKS1BSKP1SKP2MCHR1 | |
| SCHEMBL31334084 | 0.87 | MAPK1 (0.46) | MAPK1CKS1BSKP1SKP2LIPG | |
| SCHEMBL31334563 | 0.84 | CKS1B (0.47) | MAPK1CKS1BSKP1SKP2SYK | |
| SCHEMBL31334493 | 0.84 | MAPK8 (0.43) | MAPK1MCHR1ADRA2AADRA1AHRH1 | |
| SCHEMBL31334086 | 0.82 | MAPK1 (0.47) | MAPK1CKS1BSKP1SKP2MCHR1 | |
| SCHEMBL31333233 | 0.82 | NPC1 (0.43) | MAPK1CCNB2CCNE2CDK1CCNB1 | |
| SCHEMBL31333951 | 0.82 | ADORA1 (0.41) | MAPK1CDK4CCND1CCND3CDK6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709720-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | Larkspur Biosciences, Inc. (US) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233846-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | LARKSPUR BIOSCIENCES, INC. (US) | 2024-11-14 | — | — | WO | disclosed |