Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 11/20 | 0.49 |
| ▸ | JAK2 | O60674 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.44 |
| ▸ | CDK7 | P50613 | 2/20 | 0.44 |
| ▸ | CDK9 | P50750 | 2/20 | 0.44 |
| ▸ | CCNH | P51946 | 2/20 | 0.44 |
| ▸ | MNAT1 | P51948 | 2/20 | 0.44 |
| ▸ | CDK2 | P24941 | 3/20 | 0.44 |
| ▸ | CCNK | O75909 | 1/20 | 0.44 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.44 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.44 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.43 |
| ▸ | SYK | P43405 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.41 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.41 |
| ▸ | PCSK9 | Q8NBP7 | 2/20 | 0.41 |
| ▸ | JUN | P05412 | 1/20 | 0.41 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31333644 | 0.89 | JAK2 (0.45) | MAPK1JAK2BRD4CDK7CDK9 | |
| SCHEMBL31334357 | 0.89 | SYK (0.46) | MAPK1CCNT1CDK7CDK9CCNH | |
| SCHEMBL31335065 | 0.85 | MAPK1 (0.45) | MAPK1SYKPCSK9 | |
| SCHEMBL31333721 | 0.85 | MAPK1 (0.45) | MAPK1SYKPCSK9 | |
| SCHEMBL31334939 | 0.84 | MAPK1 (0.44) | MAPK1CDK2MAPK8SYKPCSK9 | |
| SCHEMBL31334050 | 0.84 | MAPK1 (0.44) | MAPK1CDK2MAPK8SYKPCSK9 | |
| SCHEMBL31334302 | 0.83 | CCNT1 (0.43) | MAPK1JAK2BRD4CCNT1CDK7 | |
| SCHEMBL31333940 | 0.83 | MAPK1 (0.48) | MAPK1SYK | |
| SCHEMBL31334428 | 0.83 | ADORA1 (0.53) | MAPK1CCNT1CDK7CDK9CCNH | |
| SCHEMBL31333658 | 0.83 | ADORA1 (0.53) | MAPK1CCNT1CDK7CDK9CCNH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709720-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | Larkspur Biosciences, Inc. (US) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233846-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | LARKSPUR BIOSCIENCES, INC. (US) | 2024-11-14 | — | — | WO | disclosed |