Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 5/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 4/20 | 0.43 |
| ▸ | JUN | P05412 | 1/20 | 0.43 |
| ▸ | DYRK2 | Q92630 | 4/20 | 0.41 |
| ▸ | MAPK8 | P45983 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | MAPK9 | P45984 | 4/20 | 0.40 |
| ▸ | CIT | O14578 | 1/20 | 0.40 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.40 |
| ▸ | STK16 | O75716 | 1/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.40 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.40 |
| ▸ | CDK11B | P21127 | 1/20 | 0.40 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.40 |
| ▸ | MAPK4 | P31152 | 1/20 | 0.40 |
| ▸ | TTK | P33981 | 1/20 | 0.40 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.40 |
| ▸ | GSK3A | P49840 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | CDK7 | P50613 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31333712 | 0.92 | SYK (0.47) | SYKMAPK10MAPK8MAPK1MAPK9 | |
| SCHEMBL31335030 | 0.90 | SYK (0.49) | SYKMAPK10JUNDYRK2MAPK1 | |
| SCHEMBL31333530 | 0.90 | SYK (0.49) | SYKMAPK10JUNDYRK2MAPK1 | |
| SCHEMBL31335040 | 0.89 | SYK (0.50) | SYKMAPK10JUNDYRK2MAPK1 | |
| SCHEMBL31334567 | 0.89 | SYK (0.50) | SYKMAPK10JUNDYRK2MAPK1 | |
| SCHEMBL31333680 | 0.87 | SYK (0.46) | SYKMAPK10JUNMAPK1ADORA1 | |
| SCHEMBL31334700 | 0.87 | SYK (0.47) | SYKDYRK2MAPK1GSK3BCDK7 | |
| SCHEMBL31333482 | 0.87 | SYK (0.48) | SYKDYRK2MAPK1MAPK9MAPK3 | |
| SCHEMBL31334814 | 0.86 | SYK (0.49) | SYKDYRK2MAPK1MAPK9GSK3A | |
| SCHEMBL31333873 | 0.85 | SYK (0.49) | SYKMAPK10MAPK8MAPK1MAPK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709720-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | Larkspur Biosciences, Inc. (US) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233846-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | LARKSPUR BIOSCIENCES, INC. (US) | 2024-11-14 | — | — | WO | disclosed |