SCHEMBL31333729

SCHEMBL31333729

CC(C)(C)OC(=O)NCC1CCN(C2CCN(c3ccc(N)cc3F)CC2)CC1

nearest known ligand 0.46

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ACACB O00763 9/20 0.46
ACACA Q13085 8/20 0.46
CKS1B P61024 1/20 0.45
SKP1 P63208 1/20 0.45
SKP2 Q13309 1/20 0.45
DRD2 P14416 2/20 0.44
SUV39H2 Q9H5I1 1/20 0.39
F10 P00742 1/20 0.39
KDM4E B2RXH2 1/20 0.39
PKM P14618 1/20 0.39
CCRL2 O00421 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13419702 0.94 ACACB (0.49) ACACBACACACKS1BSKP1SKP2
SCHEMBL31334425 0.92 DRD2 (0.48) ACACBACACACKS1BSKP1SKP2
SCHEMBL4288052 0.89 ACACB (0.47) ACACBACACACKS1BSKP1SKP2
SCHEMBL4288054 0.89 ACACB (0.47) ACACBACACACKS1BSKP1SKP2
SCHEMBL31333813 0.85 ALDH1A1 (0.44) ACACBACACACKS1BSKP1SKP2
SCHEMBL31333235 0.85 HRH3 (0.39)
SCHEMBL31333510 0.85 CKS1B (0.48) ACACBACACACKS1BSKP1SKP2
SCHEMBL13419725 0.85 SIRT2 (0.50) ACACBACACACKS1BSKP1SKP2
SCHEMBL31334895 0.85 DRD2 (0.62) ACACBACACACKS1BSKP1SKP2
SCHEMBL31334710 0.84 DRD2 (0.43) ACACBACACACKS1BSKP1SKP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4709720-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN Larkspur Biosciences, Inc. (US) 2026-03-18 EP disclosed
WO-2024233846-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN LARKSPUR BIOSCIENCES, INC. (US) 2024-11-14 WO disclosed