SCHEMBL31334895

SCHEMBL31334895

CC(C)(C)OC(=O)NC[C@H]1CC[C@H](CN2CCN(c3ccc(N)cc3F)CC2)CC1

nearest known ligand 0.62

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 6/20 0.62
JAK2 O60674 1/20 0.44
JAK1 P23458 1/20 0.44
ACACB O00763 9/20 0.44
ACACA Q13085 8/20 0.44
CKS1B P61024 1/20 0.41
SKP1 P63208 1/20 0.41
SKP2 Q13309 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13419702 0.90 ACACB (0.49) DRD2ACACBACACACKS1BSKP1
SCHEMBL27225248 0.89 DRD2 (0.62) DRD2JAK2JAK1
SCHEMBL31334425 0.89 DRD2 (0.48) DRD2ACACBACACACKS1BSKP1
SCHEMBL31334397 0.86 DRD2 (0.59) DRD2JAK2JAK1ACACBACACA
SCHEMBL4288052 0.85 ACACB (0.47) DRD2ACACBACACACKS1BSKP1
SCHEMBL4288054 0.85 ACACB (0.47) DRD2ACACBACACACKS1BSKP1
SCHEMBL31333198 0.85 DRD2 (0.43) DRD2
SCHEMBL31333486 0.85 DRD2 (0.46) DRD2
SCHEMBL31333729 0.85 ACACB (0.46) DRD2ACACBACACACKS1BSKP1
SCHEMBL31333624 0.83 DRD2 (0.53) DRD2JAK2JAK1CKS1BSKP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4709720-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN Larkspur Biosciences, Inc. (US) 2026-03-18 EP disclosed
WO-2024233846-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN LARKSPUR BIOSCIENCES, INC. (US) 2024-11-14 WO disclosed