Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.48 |
| ▸ | ATXN2 | Q99700 | 3/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | RORC | P51449 | 2/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.41 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | STS | P08842 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31333203 | 0.88 | SMN1; SMN2 (0.53) | SMN1; SMN2NPC1RAB9AENPP2CYP2C19 | |
| SCHEMBL10111508 | 0.84 | SMN1; SMN2 (0.54) | SMN1; SMN2NPC1RAB9ACYP2C19HTT | |
| SCHEMBL30553394 | 0.84 | SMN1; SMN2 (0.64) | SMN1; SMN2NPC1RAB9AENPP2ATXN2 | |
| SCHEMBL27172319 | 0.83 | ENPP2 (0.57) | SMN1; SMN2NPC1RAB9AENPP2ATXN2 | |
| SCHEMBL2455884 | 0.82 | SMN1; SMN2 (0.70) | SMN1; SMN2NPC1RAB9AENPP2CYP2C19 | |
| SCHEMBL30942476 | 0.81 | SMN1; SMN2 (0.47) | SMN1; SMN2NPC1RAB9AENPP2ATXN2 | |
| SCHEMBL31210442 | 0.81 | CCR5 (0.45) | SMN1; SMN2NPC1RAB9AENPP2ATXN2 | |
| SCHEMBL15378237 | 0.80 | SMN1; SMN2 (0.63) | SMN1; SMN2NPC1RAB9AENPP2CYP2C19 | |
| SCHEMBL616090 | 0.80 | SCD5 (0.52) | SMN1; SMN2NPC1RAB9AENPP2ATXN2 | |
| SCHEMBL14716132 | 0.80 | ENPP2 (0.56) | SMN1; SMN2NPC1RAB9AENPP2ATXN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709720-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | Larkspur Biosciences, Inc. (US) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233846-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | LARKSPUR BIOSCIENCES, INC. (US) | 2024-11-14 | — | — | WO | disclosed |