Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 6/20 | 0.44 |
| ▸ | ROCK1 | Q13464 | 6/20 | 0.44 |
| ▸ | MAPK3 | P27361 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 10/20 | 0.40 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | CDK7 | P50613 | 2/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31333369 | 0.93 | MAPK3 (0.44) | ROCK2ROCK1MAPK3MAPK1CCNA2 | |
| SCHEMBL31333935 | 0.91 | ROCK2 (0.43) | ROCK2ROCK1MAPK3MAPK1CCNA2 | |
| SCHEMBL31334078 | 0.91 | ROCK2 (0.43) | ROCK2ROCK1MAPK3MAPK1CCNA2 | |
| SCHEMBL31334678 | 0.90 | SYK (0.48) | ROCK2ROCK1MAPK3MAPK1CDK7 | |
| SCHEMBL31333461 | 0.83 | SYK (0.48) | ROCK2ROCK1MAPK3MAPK1CCNA2 | |
| SCHEMBL31333360 | 0.82 | MAPK3 (0.48) | ROCK2ROCK1MAPK3MAPK1CDK7 | |
| SCHEMBL31334355 | 0.82 | MAPK3 (0.52) | MAPK3MAPK1CDK7 | |
| SCHEMBL31334379 | 0.80 | MAPK3 (0.49) | MAPK3MAPK1CDK2CDK7 | |
| SCHEMBL31335042 | 0.80 | MAPK3 (0.49) | MAPK3MAPK1CDK2CDK7 | |
| SCHEMBL31334882 | 0.80 | SYK (0.43) | ROCK2ROCK1MAPK3MAPK1SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709720-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | Larkspur Biosciences, Inc. (US) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233846-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | LARKSPUR BIOSCIENCES, INC. (US) | 2024-11-14 | — | — | WO | disclosed |