Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 2/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.43 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 16/20 | 0.40 |
| ▸ | MAPK3 | P27361 | 2/20 | 0.39 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31334078 | 1.00 | ROCK2 (0.43) | ROCK2ROCK1IRAK1MAPK1MAPK3 | |
| SCHEMBL31333369 | 0.91 | MAPK3 (0.44) | ROCK2ROCK1MAPK1MAPK3CCNA2 | |
| SCHEMBL31333769 | 0.91 | ROCK2 (0.44) | ROCK2ROCK1MAPK1MAPK3CCNA2 | |
| SCHEMBL31334882 | 0.90 | SYK (0.43) | ROCK2ROCK1IRAK1MAPK1MAPK3 | |
| SCHEMBL31333670 | 0.90 | SYK (0.43) | ROCK2ROCK1IRAK1MAPK1MAPK3 | |
| SCHEMBL31334293 | 0.84 | IRAK1 (0.50) | IRAK1MAPK1MAPK3CDK2 | |
| SCHEMBL31333260 | 0.83 | SYK (0.43) | ROCK2ROCK1IRAK1MAPK1MAPK3 | |
| SCHEMBL31333360 | 0.81 | MAPK3 (0.48) | ROCK2ROCK1MAPK1MAPK3 | |
| SCHEMBL31333357 | 0.81 | MAPK3 (0.44) | IRAK1MAPK1MAPK3CDK2 | |
| SCHEMBL31334678 | 0.80 | SYK (0.48) | ROCK2ROCK1MAPK1MAPK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709720-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | Larkspur Biosciences, Inc. (US) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233846-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | LARKSPUR BIOSCIENCES, INC. (US) | 2024-11-14 | — | — | WO | disclosed |