Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 4/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.47 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.47 |
| ▸ | FLT3 | P36888 | 5/20 | 0.45 |
| ▸ | TYRO3 | Q06418 | 5/20 | 0.45 |
| ▸ | MERTK | Q12866 | 5/20 | 0.45 |
| ▸ | GAS6 | Q14393 | 5/20 | 0.45 |
| ▸ | GSK3A | P49840 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | AXL | P30530 | 1/20 | 0.42 |
| ▸ | MAPK10 | P53779 | 3/20 | 0.42 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.42 |
| ▸ | SYK | P43405 | 1/20 | 0.42 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.41 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.41 |
| ▸ | CDK1 | P06493 | 1/20 | 0.41 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.41 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31334186 | 0.90 | PIK3CA (0.47) | MAPK8ADORA1ADORA2AADORA2BMAPK10 | |
| SCHEMBL31333646 | 0.90 | CDK9 (0.46) | MAPK8ADORA1FLT3TYRO3MERTK | |
| SCHEMBL31333243 | 0.89 | SYK (0.46) | ADORA1FLT3TYRO3MERTKGAS6 | |
| SCHEMBL31333714 | 0.88 | DYRK2 (0.47) | SYKCCNB2CCNE2CDK1CCNB1 | |
| SCHEMBL31334964 | 0.88 | SYK (0.47) | FLT3TYRO3MERTKGAS6MAPK10 | |
| SCHEMBL31334631 | 0.88 | SYK (0.43) | MAPK8FLT3TYRO3MERTKGAS6 | |
| SCHEMBL31334756 | 0.88 | SYK (0.47) | FLT3TYRO3MERTKGAS6MAPK10 | |
| SCHEMBL31333524 | 0.86 | SYK (0.42) | ADORA1ADORA2AFLT3TYRO3MERTK | |
| SCHEMBL31334207 | 0.86 | ADORA1 (0.45) | ADORA1ADORA2AADORA2BFLT3TYRO3 | |
| SCHEMBL31334913 | 0.84 | CDK2 (0.50) | ADORA1SYKCDK1CCNB1CCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709720-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | Larkspur Biosciences, Inc. (US) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233846-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | LARKSPUR BIOSCIENCES, INC. (US) | 2024-11-14 | — | — | WO | disclosed |