Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 11/20 | 0.47 |
| ▸ | JUN | P05412 | 1/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.40 |
| ▸ | MAPK6 | Q16659 | 1/20 | 0.40 |
| ▸ | CDK1 | P06493 | 2/20 | 0.40 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.40 |
| ▸ | CDK2 | P24941 | 2/20 | 0.40 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.40 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.40 |
| ▸ | CDK7 | P50613 | 1/20 | 0.40 |
| ▸ | CDK9 | P50750 | 1/20 | 0.40 |
| ▸ | CCNH | P51946 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | JAK1 | P23458 | 1/20 | 0.40 |
| ▸ | JAK3 | P52333 | 1/20 | 0.40 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.40 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.40 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.40 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.40 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31334964 | 1.00 | SYK (0.47) | SYKJUNMAPK10MAPK6CDK1 | |
| SCHEMBL31335015 | 0.92 | SYK (0.44) | SYKMAPK6CDK1CCNB1CDK2 | |
| SCHEMBL31333243 | 0.92 | SYK (0.46) | SYKJUNMAPK10CDK1CCNB1 | |
| SCHEMBL31333998 | 0.91 | SYK (0.48) | SYKCDK1CCNB1CDK2CCNT1 | |
| SCHEMBL31334543 | 0.90 | SYK (0.44) | SYKCDK1CCNB1CDK2CCNT1 | |
| SCHEMBL31333524 | 0.89 | SYK (0.42) | SYKJUNMAPK10CDK1CCNB1 | |
| SCHEMBL31334031 | 0.88 | MAPK8 (0.49) | SYKJUNMAPK10CDK1CCNB1 | |
| SCHEMBL31333646 | 0.88 | CDK9 (0.46) | SYKMAPK10CDK1CCNB1CDK2 | |
| SCHEMBL31334631 | 0.87 | SYK (0.43) | SYKJUNMAPK10CDK1CCNB1 | |
| SCHEMBL31334567 | 0.87 | SYK (0.50) | SYKJUNMAPK10MAPK6CDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709720-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | Larkspur Biosciences, Inc. (US) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233846-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | LARKSPUR BIOSCIENCES, INC. (US) | 2024-11-14 | — | — | WO | disclosed |