SCHEMBL31334737

SCHEMBL31334737

NC(=O)C1CCCC(Nc2ncc(F)c(-c3cccc(N4CCCOC4=O)c3)n2)C1

nearest known ligand 0.39

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 5/20 0.39
SYK P43405 6/20 0.37
PIK3CD O00329 2/20 0.37
MAPK3 P27361 2/20 0.37
CCNA2 P20248 2/20 0.37
CDK2 P24941 2/20 0.37
CAMK1D Q8IU85 1/20 0.37
CDK7 P50613 2/20 0.36
AURKA O14965 1/20 0.34
CCNA1 P78396 1/20 0.34
CDK4 P11802 1/20 0.34
CDK6 Q00534 1/20 0.34
DYRK2 Q92630 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31333589 0.93 MAPK1 (0.39) MAPK1SYKPIK3CDMAPK3CCNA2
SCHEMBL31334159 0.93 MAPK1 (0.39) MAPK1SYKPIK3CDMAPK3CCNA2
SCHEMBL31334975 0.92 MAPK1 (0.41) MAPK1SYKPIK3CDMAPK3CCNA2
SCHEMBL31334417 0.92 MAPK1 (0.41) MAPK1SYKPIK3CDMAPK3CCNA2
SCHEMBL31333650 0.91 IRAK1 (0.41) MAPK1PIK3CDMAPK3CCNA2CDK2
SCHEMBL31333990 0.88 MAPK1 (0.45) MAPK1PIK3CDMAPK3CCNA2CDK2
SCHEMBL31334114 0.88 MAP4K1 (0.42) MAPK1SYKPIK3CDMAPK3CCNA2
SCHEMBL31334703 0.87 MAPK1 (0.42) MAPK1SYKMAPK3CCNA2CDK2
SCHEMBL31333597 0.86 MAPK1 (0.41) MAPK1SYKPIK3CDMAPK3CCNA2
SCHEMBL31333290 0.85 CDK9 (0.41) MAPK1SYKPIK3CDMAPK3CCNA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4709720-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN Larkspur Biosciences, Inc. (US) 2026-03-18 EP disclosed
WO-2024233846-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN LARKSPUR BIOSCIENCES, INC. (US) 2024-11-14 WO disclosed