Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.48 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.43 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24351663 | 0.88 | HRH3 (0.51) | HRH3NR1H2USP30GPR119SMN1; SMN2 | |
| SCHEMBL22165053 | 0.87 | NR1H2 (0.46) | HRH3NR1H2USP30GPR119HDAC2 | |
| SCHEMBL31548466 | 0.87 | NR1H2 (0.46) | HRH3NR1H2USP30GPR119HDAC2 | |
| SCHEMBL31333261 | 0.85 | HRH3 (0.51) | HRH3NR1H2USP30GPR119SMN1; SMN2 | |
| SCHEMBL25024580 | 0.85 | HDAC2 (0.49) | HRH3NR1H2USP30HDAC2HDAC1 | |
| SCHEMBL31334221 | 0.85 | HRH3 (0.40) | HRH3SMN1; SMN2ALDH1A1LMNAMAPT | |
| SCHEMBL25169824 | 0.85 | ALDH1A1 (0.47) | HRH3SMN1; SMN2ALDH1A1LMNAMAPT | |
| SCHEMBL4299226 | 0.83 | CYP11B2 (0.48) | HRH3NR1H2USP30HDAC2HDAC1 | |
| SCHEMBL23783164 | 0.82 | GPR119 (0.58) | NR1H2GPR119SMN1; SMN2 | |
| SCHEMBL2886408 | 0.81 | CYP11B2 (0.52) | HRH3NR1H2HDAC2HDAC1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709720-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | Larkspur Biosciences, Inc. (US) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233846-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | LARKSPUR BIOSCIENCES, INC. (US) | 2024-11-14 | — | — | WO | disclosed |