Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMARCA2 | P51531 | 1/20 | 0.40 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.40 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | IDH2 | P48735 | 3/20 | 0.39 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | DRD5 | P21918 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.38 |
| ▸ | DHFR | P00374 | 1/20 | 0.38 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.38 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31334501 | 1.00 | SMARCA2 (0.40) | SMARCA2SMARCA4PBRM1ARIDH2 | |
| SCHEMBL30252765 | 0.90 | AR (0.48) | ARSLC18A3ATML3MBTL1NOTUM | |
| SCHEMBL365887 | 0.90 | AR (0.48) | ARSLC18A3ATML3MBTL1NOTUM | |
| SCHEMBL28996058 | 0.90 | AR (0.48) | ARSLC18A3ATML3MBTL1NOTUM | |
| SCHEMBL21683097 | 0.83 | ALOX5 (0.43) | SLC18A3ALOX5ATML3MBTL1ALDH1A1 | |
| SCHEMBL3027755 | 0.80 | USP2 (0.42) | SMARCA2SMARCA4PBRM1ARALDH1A1 | |
| SCHEMBL22290739 | 0.80 | DHFR (0.44) | SLC18A3ALOX5ATML3MBTL1ALDH1A1 | |
| SCHEMBL3027753 | 0.80 | USP2 (0.42) | SMARCA2SMARCA4PBRM1ARALDH1A1 | |
| SCHEMBL6628944 | 0.80 | ALDH1A1 (0.53) | SMARCA2SMARCA4PBRM1SLC18A3L3MBTL1 | |
| SCHEMBL3449455 | 0.80 | NOTUM (0.60) | ALDH1A1NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709720-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | Larkspur Biosciences, Inc. (US) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233846-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | LARKSPUR BIOSCIENCES, INC. (US) | 2024-11-14 | — | — | WO | disclosed |