Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.47 |
| ▸ | HTR2A | P28223 | 2/20 | 0.47 |
| ▸ | HTR2C | P28335 | 2/20 | 0.47 |
| ▸ | HTR2B | P41595 | 2/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | ACHE | P22303 | 3/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12731682 | 0.94 | KDM4E (0.45) | DRD2HTR2AHTR2CHTR2BSIGMAR1 | |
| SCHEMBL12731242 | 0.94 | KDM4E (0.45) | DRD2HTR2AHTR2CHTR2BSIGMAR1 | |
| SCHEMBL12731241 | 0.94 | KDM4E (0.45) | DRD2HTR2AHTR2CHTR2BSIGMAR1 | |
| SCHEMBL803672 | 0.89 | SIGMAR1 (0.59) | DRD2HTR2AHTR2CHTR2BSIGMAR1 | |
| SCHEMBL21026882 | 0.89 | KMT2A (0.49) | DRD2HTR2AHTR2CHTR2BSIGMAR1 | |
| SCHEMBL31334937 | 0.85 | DRD2 (0.54) | DRD2HTR2AHTR2CHTR2BSIGMAR1 | |
| SCHEMBL31701660 | 0.83 | SMN1; SMN2 (0.48) | HTR2AHTR2CHTR2BSIGMAR1SMN1; SMN2 | |
| SCHEMBL3815654 | 0.82 | SIGMAR1 (0.51) | DRD2HTR2AHTR2CHTR2BSIGMAR1 | |
| SCHEMBL31333511 | 0.82 | ALDH1A1 (0.50) | KDM4EALDH1A1ACHERECQLSMN1; SMN2 | |
| SCHEMBL7507555 | 0.82 | SIGMAR1 (0.51) | DRD2HTR2AHTR2CHTR2BSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709720-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | Larkspur Biosciences, Inc. (US) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233846-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | LARKSPUR BIOSCIENCES, INC. (US) | 2024-11-14 | — | — | WO | disclosed |