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SCHEMBL31334472

SCHEMBL31334472

CC(C)(C)OC(=O)N1CCC(OC2CCN(c3ccc(N)cc3F)CC2)CC1

nearest known ligand 0.57

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ GPR119 Q8TDV5 15/20 0.57
▸ NR1H2 P55055 1/20 0.46
▸ SMN1; SMN2 Q16637 1/20 0.46
▸ DPP4 P27487 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23783164 0.91 GPR119 (0.58) GPR119NR1H2SMN1; SMN2
SCHEMBL30207450 0.89 GPR119 (0.51) GPR119NR1H2SMN1; SMN2DPP4
SCHEMBL31333808 0.88 GPR119 (0.48) GPR119NR1H2SMN1; SMN2DPP4
SCHEMBL660403 0.87 NR1H2 (0.53) GPR119NR1H2SMN1; SMN2
SCHEMBL29508938 0.87 NR1H2 (0.53) GPR119NR1H2SMN1; SMN2
SCHEMBL31333261 0.86 HRH3 (0.51) GPR119NR1H2SMN1; SMN2DPP4
SCHEMBL24351663 0.86 HRH3 (0.51) GPR119NR1H2SMN1; SMN2DPP4
SCHEMBL31334387 0.83 ALDH1A1 (0.54) GPR119SMN1; SMN2
SCHEMBL23783347 0.83 HRH3 (0.47) GPR119NR1H2SMN1; SMN2DPP4
SCHEMBL21786071 0.83 CNR1 (0.44) GPR119NR1H2SMN1; SMN2DPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4709720-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN Larkspur Biosciences, Inc. (US) 2026-03-18 — — EP disclosed
WO-2024233846-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN LARKSPUR BIOSCIENCES, INC. (US) 2024-11-14 — — WO disclosed