Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 1/20 | 0.39 |
| ▸ | ATRIP | Q8WXE1 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 4/20 | 0.38 |
| ▸ | IDH1 | O75874 | 6/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.32 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30444356 | 0.91 | IDH1 (0.42) | ATRATRIPPIM1IDH1 | |
| SCHEMBL20574851 | 0.91 | IDH1 (0.42) | ATRATRIPPIM1IDH1 | |
| SCHEMBL31334843 | 0.79 | ATR (0.37) | ATRATRIPPIM1IDH1PIK3CA | |
| SCHEMBL29348995 | 0.78 | AKR1C3 (0.44) | ATRATRIPPIM1ALDH1A1KDM1A | |
| SCHEMBL24135526 | 0.77 | PARP1 (0.48) | PIM1IDH1ALDH1A1ROCK1MAP3K14 | |
| SCHEMBL31333194 | 0.76 | PARP1 (0.47) | ATRATRIPPIM1IDH1ROCK1 | |
| SCHEMBL16094570 | 0.73 | PTGS2 (0.42) | ATRATRIPPIK3CAPIK3CD | |
| SCHEMBL12859179 | 0.73 | CYP3A4 (0.48) | PIM1IDH1ALDH1A1SMN1; SMN2 | |
| SCHEMBL19280392 | 0.73 | HSD11B1 (0.50) | PIK3CDALDH1A1KDM1A | |
| SCHEMBL31334558 | 0.72 | ALOX5 (0.43) | ATRATRIPPIM1IDH1PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709720-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | Larkspur Biosciences, Inc. (US) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233846-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | LARKSPUR BIOSCIENCES, INC. (US) | 2024-11-14 | — | — | WO | disclosed |