Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | CKS1B | P61024 | 1/20 | 0.46 |
| ▸ | SKP1 | P63208 | 1/20 | 0.46 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
| ▸ | ACACA | Q13085 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5652480 | 0.94 | MAPT (0.58) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL30738841 | 0.86 | MAPT (0.54) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL31333982 | 0.86 | SIRT6 (0.46) | MAPTALDH1A1MEN1KMT2ACKS1B | |
| SCHEMBL31333813 | 0.86 | ALDH1A1 (0.44) | MAPTALDH1A1LMNAKMT2ACKS1B | |
| SCHEMBL31333510 | 0.86 | CKS1B (0.48) | CKS1BSKP1SKP2DRD2NAMPT | |
| SCHEMBL30198676 | 0.80 | CKS1B (0.54) | MAPTCKS1BSKP1SKP2DRD2 | |
| SCHEMBL29106557 | 0.80 | ALDH1A1 (0.55) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL12916519 | 0.80 | GPR119 (0.57) | MEN1KMT2ACKS1BSKP1SKP2 | |
| SCHEMBL30722421 | 0.79 | MAPT (0.78) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL13419653 | 0.79 | ALDH1A1 (0.48) | MAPTALDH1A1LMNAKMT2ACKS1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709720-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | Larkspur Biosciences, Inc. (US) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233846-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | LARKSPUR BIOSCIENCES, INC. (US) | 2024-11-14 | — | — | WO | disclosed |