SCHEMBL31334759

SCHEMBL31334759

O=CC[C@H]1CC[C@H](C(=O)N2CCC(Nc3ncc(Cl)c(-c4cccc(-c5ccc(F)cc5)c4)n3)CC2)CC1

nearest known ligand 0.44

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 20/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31335044 0.87 MAPK10 (0.48) MAPK1
SCHEMBL31333538 0.87 MAPK10 (0.48) MAPK1
SCHEMBL31333401 0.87 MAPK1 (0.50) MAPK1
SCHEMBL31334032 0.87 MAPK1 (0.46) MAPK1
SCHEMBL31333959 0.85 MAPK1 (0.48) MAPK1
SCHEMBL31334224 0.82 MAPK1 (0.49) MAPK1
SCHEMBL31335014 0.82 CCNT1 (0.49) MAPK1
SCHEMBL31334722 0.80 MAPK1 (0.53) MAPK1
SCHEMBL31334860 0.79 MAPK1 (0.56) MAPK1
SCHEMBL31335038 0.79 CDK2 (0.54) MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4709720-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN Larkspur Biosciences, Inc. (US) 2026-03-18 EP disclosed
WO-2024233846-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN LARKSPUR BIOSCIENCES, INC. (US) 2024-11-14 WO disclosed