SCHEMBL31335014

SCHEMBL31335014

CC(C)(C)OC(=O)N1CCC(C(=O)N2CCC(Nc3ncc(Cl)c(-c4cccc(-c5ccc(F)cc5)c4)n3)CC2)CC1

nearest known ligand 0.49

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CCNT1 O60563 1/20 0.49
MAPK1 P28482 10/20 0.47
MAPK8 P45983 4/20 0.46
MAPK9 P45984 4/20 0.46
MAPK10 P53779 2/20 0.46
PTPN2 P17706 1/20 0.44
PTPN1 P18031 1/20 0.44
PTPN6 P29350 1/20 0.44
FNTA P49354 1/20 0.44
FNTB P49356 1/20 0.44
DNMT3A Q9Y6K1 1/20 0.43
STS P08842 1/20 0.43
JUN P05412 3/20 0.42
CDK2 P24941 3/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31334054 0.96 CCNT1 (0.52) CCNT1MAPK1MAPK8MAPK9MAPK10
SCHEMBL31334616 0.94 MAPK8 (0.51) CCNT1MAPK1MAPK8MAPK9MAPK10
SCHEMBL31334296 0.92 MAPK1 (0.46) CCNT1MAPK1MAPK8MAPK9MAPK10
SCHEMBL31333535 0.91 MAPK1 (0.46) CCNT1MAPK1MAPK8MAPK9MAPK10
SCHEMBL31333391 0.90 MAPK1 (0.53) CCNT1MAPK1MAPK8MAPK9MAPK10
SCHEMBL31333217 0.89 MAPK8 (0.54) CCNT1MAPK1MAPK8MAPK9MAPK10
SCHEMBL31334839 0.89 CCNT1 (0.48) CCNT1MAPK1MAPK8MAPK9MAPK10
SCHEMBL31334277 0.88 MAPK1 (0.43) CCNT1MAPK1MAPK8MAPK9MAPK10
SCHEMBL31334823 0.88 DYRK2 (0.52) CCNT1MAPK1PTPN2PTPN1PTPN6
SCHEMBL31334032 0.88 MAPK1 (0.46) MAPK1MAPK8MAPK9MAPK10JUN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4709720-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN Larkspur Biosciences, Inc. (US) 2026-03-18 EP disclosed
WO-2024233846-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN LARKSPUR BIOSCIENCES, INC. (US) 2024-11-14 WO disclosed