SCHEMBL31334803

SCHEMBL31334803

CC(C)(C)OC(=O)CC1CCN(CC2CCN(c3ccc(NC4CCC(=O)NC4=O)cc3F)CC2)CC1

nearest known ligand 0.47

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 17/20 0.47
DDB1 Q16531 16/20 0.47
LMNA P02545 1/20 0.38
HDAC8 Q9BY41 1/20 0.38
CYP3A4 P08684 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31334208 0.95 CRBN (0.49) CRBNDDB1HDAC8
SCHEMBL24126005 0.95 CRBN (0.51) CRBNDDB1
SCHEMBL31334549 0.91 CRBN (0.48) CRBNDDB1LMNAHDAC8
SCHEMBL24125412 0.91 CRBN (0.49) CRBNDDB1
SCHEMBL31333732 0.91 CRBN (0.47) CRBNDDB1
SCHEMBL31333707 0.91 CRBN (0.47) CRBNDDB1LMNAHDAC8CYP3A4
SCHEMBL31334160 0.90 DDB1 (0.57) CRBNDDB1
SCHEMBL31334275 0.89 CRBN (0.46) CRBNDDB1
SCHEMBL31333201 0.88 CRBN (0.44) CRBNDDB1LMNA
SCHEMBL31701449 0.87 DDB1 (0.59) CRBNDDB1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4709720-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN Larkspur Biosciences, Inc. (US) 2026-03-18 EP disclosed
WO-2024233846-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN LARKSPUR BIOSCIENCES, INC. (US) 2024-11-14 WO disclosed