SCHEMBL31334296

SCHEMBL31334296

CC(C)(C)OC(=O)N1CCC(C(=O)N[C@H]2CC[C@H](Nc3ncc(Cl)c(-c4cccc(-c5ccc(F)cc5)c4)n3)CC2)CC1

nearest known ligand 0.46

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 7/20 0.46
CCNT1 O60563 1/20 0.46
PTPN2 P17706 1/20 0.45
PTPN1 P18031 1/20 0.45
PTPN6 P29350 1/20 0.45
MAPK8 P45983 1/20 0.44
MAPK9 P45984 1/20 0.44
MAPK10 P53779 1/20 0.44
STS P08842 2/20 0.43
EPHX2 P34913 2/20 0.43
USP30 Q70CQ3 1/20 0.42
DYRK2 Q92630 1/20 0.41
DNMT3A Q9Y6K1 1/20 0.41
DGAT2 Q96PD7 2/20 0.41
SUV39H2 Q9H5I1 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31334277 0.96 MAPK1 (0.43) MAPK1CCNT1PTPN2PTPN1PTPN6
SCHEMBL31334054 0.93 CCNT1 (0.52) MAPK1CCNT1MAPK8MAPK9MAPK10
SCHEMBL31335014 0.92 CCNT1 (0.49) MAPK1CCNT1PTPN2PTPN1PTPN6
SCHEMBL31334026 0.86 MAPK1 (0.48) MAPK1
SCHEMBL31333535 0.86 MAPK1 (0.46) MAPK1CCNT1PTPN2PTPN1PTPN6
SCHEMBL31333217 0.86 MAPK8 (0.54) MAPK1CCNT1MAPK8MAPK9MAPK10
SCHEMBL31334839 0.86 CCNT1 (0.48) MAPK1CCNT1MAPK8MAPK9MAPK10
SCHEMBL31334616 0.86 MAPK8 (0.51) MAPK1CCNT1MAPK8MAPK9MAPK10
SCHEMBL31333916 0.85 MAPK1 (0.53) MAPK1CCNT1MAPK8MAPK9MAPK10
SCHEMBL31334823 0.85 DYRK2 (0.52) MAPK1CCNT1PTPN2PTPN1PTPN6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4709720-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN Larkspur Biosciences, Inc. (US) 2026-03-18 EP disclosed
WO-2024233846-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN LARKSPUR BIOSCIENCES, INC. (US) 2024-11-14 WO disclosed