SCHEMBL31335006

SCHEMBL31335006

CC(=O)N1CCC(Nc2ncc(F)c(-c3ccnc(C(C)(C)O)c3)n2)CC1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDK2 P24941 7/20 0.45
MAPK1 P28482 6/20 0.45
GSK3B P49841 2/20 0.45
PRKD3 O94806 1/20 0.45
MAP4K4 O95819 1/20 0.45
MAPK8 P45983 1/20 0.45
MAPK9 P45984 1/20 0.45
CSNK1A1 P48729 1/20 0.45
CSNK1D P48730 1/20 0.45
GSK3A P49840 1/20 0.45
CSNK1G2 P78368 1/20 0.45
TAOK1 Q7L7X3 1/20 0.45
MINK1 Q8N4C8 1/20 0.45
PRKD2 Q9BZL6 1/20 0.45
CLK4 Q9HAZ1 1/20 0.45
CSNK1G1 Q9HCP0 1/20 0.45
CSNK1G3 Q9Y6M4 1/20 0.45
MAPK14 Q16539 1/20 0.45
DYRK2 Q92630 4/20 0.45
CDK4 P11802 3/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31334985 0.87 MAPK8 (0.44) CDK2MAPK1MAPK8MAPK9MAPK14
SCHEMBL31334321 0.85 MAPK1 (0.42) CDK2MAPK1DYRK2CDK4CCND1
SCHEMBL31333665 0.84 MAPK1 (0.42) CDK2MAPK1MAPK8MAPK9CDK4
SCHEMBL31333476 0.84 CDK9 (0.46) CDK2MAPK1MAPK8MAPK9CSNK1A1
SCHEMBL31333890 0.83 MAPK1 (0.43) CDK2MAPK1MAPK8DYRK2CDK4
SCHEMBL31333526 0.83 MAPK1 (0.43) CDK2MAPK1MAPK8DYRK2CDK4
SCHEMBL31334086 0.82 MAPK1 (0.47) CDK2MAPK1DYRK2CDK4CCND1
SCHEMBL31334440 0.82 IRAK1 (0.49) CDK2MAPK1GSK3BMAPK14DYRK2
SCHEMBL31334347 0.81 DYRK2 (0.47) CDK2MAPK1GSK3BPRKD3MAP4K4
SCHEMBL31334598 0.81 MAPK3 (0.41) CDK2MAPK1DYRK2CDK4CCND1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4709720-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN Larkspur Biosciences, Inc. (US) 2026-03-18 EP disclosed
WO-2024233846-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN LARKSPUR BIOSCIENCES, INC. (US) 2024-11-14 WO disclosed