Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK1 | P23458 | 4/20 | 0.36 |
| ▸ | JAK2 | O60674 | 3/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.32 |
| ▸ | CDK9 | P50750 | 2/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.30 |
| ▸ | FEN1 | P39748 | 2/20 | 0.30 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.30 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31333974 | 1.00 | JAK1 (0.36) | JAK1JAK2GPR119NR1H2CCNT1 | |
| SCHEMBL31333480 | 0.85 | GPR119 (0.38) | GPR119NR1H2OPRL1CYP3A4CYP2C9 | |
| SCHEMBL31334947 | 0.81 | SLC9A1 (0.43) | GPR119NR1H2DPP4OPRL1CYP3A4 | |
| SCHEMBL31334214 | 0.79 | CRBN (0.44) | — | |
| SCHEMBL31334354 | 0.79 | CRBN (0.44) | — | |
| SCHEMBL31333749 | 0.78 | GPR119 (0.41) | GPR119NR1H2OPRL1KCNH2GRM2 | |
| SCHEMBL24125418 | 0.77 | NR1H2 (0.34) | JAK1JAK2GPR119NR1H2CCNT1 | |
| SCHEMBL29196975 | 0.77 | NR1H2 (0.34) | JAK1JAK2GPR119NR1H2CCNT1 | |
| SCHEMBL29535803 | 0.76 | GPR119 (0.56) | GPR119NR1H2DPP4ALOX5APFEN1 | |
| SCHEMBL6395680 | 0.76 | GPR119 (0.56) | GPR119NR1H2DPP4ALOX5APFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709720-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | Larkspur Biosciences, Inc. (US) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233846-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | LARKSPUR BIOSCIENCES, INC. (US) | 2024-11-14 | — | — | WO | disclosed |