SCHEMBL31333749

SCHEMBL31333749

CC(C)(C)OC(=O)[C@H]1CC[C@H](CN2CCC(c3ccc(N)cc3F)CC2)CC1

nearest known ligand 0.41

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 2/20 0.41
ACHE P22303 2/20 0.40
HTR4 Q13639 2/20 0.40
DRD2 P14416 3/20 0.39
OPRK1 P41145 1/20 0.39
HRH1 P35367 4/20 0.38
CCR3 P51677 4/20 0.38
OPRL1 P41146 1/20 0.38
GRM2 Q14416 1/20 0.37
HTR2A P28223 1/20 0.37
HTR2C P28335 1/20 0.37
HTR2B P41595 1/20 0.37
SIGMAR1 Q99720 1/20 0.37
NR1H2 P55055 1/20 0.36
CNR1 P21554 1/20 0.36
KCNH2 Q12809 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20076070 0.86 GPR119 (0.55) GPR119ACHEHTR4NR1H2CNR1
SCHEMBL31333559 0.85 DRD2 (0.54) DRD2OPRL1HTR2A
SCHEMBL31333486 0.85 DRD2 (0.46) ACHEHTR4DRD2HRH1CCR3
SCHEMBL31334947 0.85 SLC9A1 (0.43) GPR119OPRL1NR1H2KCNH2
SCHEMBL31333480 0.85 GPR119 (0.38) GPR119DRD2OPRL1GRM2NR1H2
SCHEMBL31334725 0.83 ACHE (0.43) ACHEHTR4DRD2HRH1CCR3
SCHEMBL25121848 0.81 DRD4 (0.43) GPR119HTR4OPRL1GRM2NR1H2
SCHEMBL30313449 0.81 DRD4 (0.43) GPR119HTR4OPRL1GRM2NR1H2
SCHEMBL31333974 0.78 JAK1 (0.36) GPR119OPRL1GRM2NR1H2KCNH2
SCHEMBL31335100 0.78 JAK1 (0.36) GPR119OPRL1GRM2NR1H2KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4709720-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN Larkspur Biosciences, Inc. (US) 2026-03-18 EP disclosed
WO-2024233846-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN LARKSPUR BIOSCIENCES, INC. (US) 2024-11-14 WO disclosed