Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.62 |
| ▸ | TACR2 | P21452 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | FDPS | P14324 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3464451 | 0.92 | FDPS (0.54) | ALDH1A1TACR2HPGDTDP1L3MBTL1 | |
| SCHEMBL493684 | 0.88 | ALDH1A1 (0.73) | ALDH1A1TACR2HPGDTDP1L3MBTL1 | |
| SCHEMBL30159697 | 0.88 | ALDH1A1 (0.73) | ALDH1A1TACR2HPGDTDP1L3MBTL1 | |
| SCHEMBL29652045 | 0.86 | FDPS (0.71) | ALDH1A1HPGDTDP1MAPTNPSR1 | |
| SCHEMBL1748511 | 0.86 | ALDH1A1 (0.66) | ALDH1A1HPGDTDP1MAPTNPSR1 | |
| SCHEMBL1396839 | 0.86 | FDPS (0.71) | ALDH1A1HPGDTDP1MAPTNPSR1 | |
| SCHEMBL25192060 | 0.85 | ALDH1A1 (0.59) | ALDH1A1TACR2HPGDTDP1L3MBTL1 | |
| SCHEMBL25187353 | 0.85 | ALDH1A1 (0.59) | ALDH1A1TACR2HPGDTDP1L3MBTL1 | |
| SCHEMBL30485565 | 0.85 | ALDH1A1 (0.59) | ALDH1A1TACR2HPGDTDP1L3MBTL1 | |
| Ethyl Vanillin SCHEMBL28478773 | 0.82 | ALDH1A1 (0.78) | ALDH1A1HPGDTDP1L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2142528-B1 | 1-(1-BENZYLPIPERIDIN-4-YL)BENZIMIDAZ0LE -5-CARBOXYLIC ACID DERIVATIVES FOR THE TREATMENT OF DIABETES MELLITUS | HOFFMANN LA ROCHE (CH) | 2010-07-07 | — | — | EP | disclosed |
| US-7393367-B2 | Agent for dyeing keratin-based fibers | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2008-07-01 | — | — | US | disclosed |
| US-7393367-B2 | Agent for dyeing keratin-based fibers | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2008-07-01 | — | — | US | disclosed |
| US-7393367-B2 | Agent for dyeing keratin-based fibers | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2008-07-01 | — | — | US | disclosed |
| US-20080104772-A1 | AGENT FOR DYEING KERATIN-BASED FIBERS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2008-05-08 | — | — | US | disclosed |
| US-20080104772-A1 | AGENT FOR DYEING KERATIN-BASED FIBERS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2008-05-08 | — | — | US | disclosed |
| US-20080104772-A1 | AGENT FOR DYEING KERATIN-BASED FIBERS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2008-05-08 | — | — | US | disclosed |
| EP-1879660-A1 | AGENT FOR DYEING KERATIN-BASED FIBRES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006119819-A1 | AGENT FOR DYEING KERATIN-BASED FIBRES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2006-11-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080104772-A1 | AGENT FOR DYEING KERATIN-BASED FIBERS | KRT18, KAT5, H1-5 | ALDH1A1 1093/4885TACR2 268/4885HPGD 1814/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.