Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.73 |
| ▸ | TACR2 | P21452 | 1/20 | 0.69 |
| ▸ | MAPT | P10636 | 3/20 | 0.64 |
| ▸ | HPGD | P15428 | 2/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.62 |
| ▸ | FDPS | P14324 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30159697 | 1.00 | ALDH1A1 (0.73) | ALDH1A1TACR2MAPTHPGDTDP1 | |
| SCHEMBL11212209 | 0.91 | ALDH1A1 (0.64) | ALDH1A1TACR2MAPTHPGDTDP1 | |
| SCHEMBL4948728 | 0.91 | ALDH1A1 (0.64) | ALDH1A1TACR2MAPTHPGDTDP1 | |
| SCHEMBL754958 | 0.91 | ALDH1A1 (0.72) | ALDH1A1TACR2MAPTHPGDTDP1 | |
| SCHEMBL30416638 | 0.91 | ALDH1A1 (0.72) | ALDH1A1TACR2MAPTHPGDTDP1 | |
| SCHEMBL356800 | 0.91 | FDPS (0.77) | ALDH1A1TACR2MAPTHPGDTDP1 | |
| SCHEMBL13221144 | 0.90 | ALDH1A1 (0.63) | ALDH1A1TACR2MAPTHPGDTDP1 | |
| SCHEMBL2679839 | 0.90 | ALDH1A1 (0.62) | ALDH1A1TACR2MAPTHPGDTDP1 | |
| SCHEMBL23457684 | 0.89 | ALDH1A1 (0.63) | ALDH1A1TACR2MAPTHPGDTDP1 | |
| SCHEMBL25587623 | 0.89 | ALDH1A1 (0.63) | ALDH1A1TACR2MAPTHPGDTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 442 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11596716-B2 | Compounds and matrices for use in bone growth and repair | HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) | 2023-03-07 | — | — | US | claimed |
| US-20210138117-A1 | COMPOUNDS AND MATRICES FOR USE IN BONE GROWTH AND REPAIR | HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) | 2021-05-13 | — | — | US | claimed |
| EP-2199290-B1 | Method of nucleating a polyolefin composition with acetal-based compounds | MILLIKEN & CO (US) | 2018-06-06 | — | — | EP | claimed |
| EP-3038621-A2 | COMPOUNDS AND MATRICES FOR USE IN BONE GROWTH AND REPAIR | Human Biomolecular Research Institute (US) | 2016-07-06 | — | — | EP | claimed |
| EP-2663542-B1 | PROCESS FOR THE PREPARATION OF ALDITOL ACETALS | RELIANCE IND LTD (IN) | 2016-07-06 | — | — | EP | claimed |
| US-20160038641-A1 | COMPOUNDS AND MATRICES FOR USE IN BONE GROWTH AND REPAIR | HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) | 2016-02-11 | — | — | US | claimed |
| US-9029575-B2 | Process for preparation of acetals | RELIANCE INDUSTRIES LIMITED (IN) | 2015-05-12 | — | — | US | claimed |
| US-8969595-B2 | Method of making diacetal compound in aqueous medium | RELIANCE INDUSTRIES LIMITED (IN) | 2015-03-03 | — | — | US | claimed |
| US-8871954-B2 | Process for the preparation of alditol acetals | RELIANCE INDUSTRIES LIMITED (IN) | 2014-10-28 | — | — | US | claimed |
| WO-2014146039-A2 | COMPOUNDS AND MATRICES FOR USE IN BONE GROWTH AND REPAIR | HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) | 2014-09-18 | — | — | WO | claimed |
| WO-2005111134-A2 | METHOD OF NUCLEATING A POLYOLEFIN COMPOSITION WITH ACETAL-BASED COMPOUNDS | MILLIKEN & COMPANY (US) | 2005-11-24 | — | — | WO | claimed |
| WO-2005108479-A2 | ACETAL-BASED COMPOSITIONS | MILLIKEN & COMPANY (US) | 2005-11-17 | — | — | WO | claimed |
| US-20050239928-A1 | Acetal-based compositions | MILLIKEN & COMPANY | 2005-10-27 | — | — | US | claimed |
| US-20050239926-A1 | Method of nucleating a polyolefin composition with acetal-based compounds | MILLIKEN & COMPANY | 2005-10-27 | — | — | US | claimed |
| EP-1390336-A1 | METHOD FOR PRODUCING AROMATIC ALDEHYDES AND KETONES BY THE CATALYTIC OXIDATION OF ALKYL-AROMATIC COMPOUNDS | DSM Fine Chemicals Austria Nfg GmbH & Co KG (AT) | 2004-02-25 | — | — | EP | claimed |
| US-20030124157-A1 | Compositions containing aromatic aldehydes and their use in treatments | ALLERGAN, INC. | 2003-07-03 | — | — | US | claimed |
| WO-2002096849-A1 | METHOD FOR PRODUCING AROMATIC ALDEHYDES AND KETONES BY THE CATALYTIC OXIDATION OF ALKYL-AROMATIC COMPOUNDS | DSM FINE CHEMICALS AUSTRIA NFG GMBH & CO KG (AT) | 2002-12-05 | — | — | WO | claimed |
| US-4473713-A | Hydrolysis of aryl-aliphatic ethers | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1984-09-25 | — | — | US | claimed |
| EP-0031253-B1 | PROCESS FOR PREPARING 3,4-SUBSTITUTED BENZALDEHYDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1983-10-05 | — | — | EP | claimed |
| EP-0031253-A1 | Process for preparing 3,4-substituted benzaldehydes | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1981-07-01 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11596716-B2 | Compounds and matrices for use in bone growth and repair | BMP2, BMP4, BMP6 | ALDH1A1 1413/4885TACR2 1363/4885MAPT 4739/4885 |
| US-20030124157-A1 | Compositions containing aromatic aldehydes and their use in treatments | TYR, ALDH2, AOX1 | ALDH1A1 4/4885TACR2 1043/4885MAPT 333/4885 |
| US-20210138117-A1 | COMPOUNDS AND MATRICES FOR USE IN BONE GROWTH AND REPAIR | BMP2, BMP4, BMP6 | ALDH1A1 1413/4885TACR2 1363/4885MAPT 4739/4885 |
| US-20050239928-A1 | Acetal-based compositions | PCNA, RAD51, AR | ALDH1A1 575/4885TACR2 4807/4885MAPT 2567/4885 |
| US-20160038641-A1 | COMPOUNDS AND MATRICES FOR USE IN BONE GROWTH AND REPAIR | BMP2, BMP4, BMP6 | ALDH1A1 1157/4885TACR2 2081/4885MAPT 4725/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.