Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRAP1 | Q12931 | 5/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 15/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 9/20 | 0.38 |
| ▸ | HSP90B1 | P14625 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31335611 | 0.94 | TRAP1 (0.39) | TRAP1HSP90AA1HSP90AB1HSP90B1 | |
| SCHEMBL31335521 | 0.89 | TRAP1 (0.43) | TRAP1HSP90AA1HSP90AB1HSP90B1 | |
| SCHEMBL31335516 | 0.87 | BTK (0.44) | TRAP1HSP90AA1HSP90AB1HSP90B1 | |
| SCHEMBL31335779 | 0.84 | SLC6A9 (0.35) | TRAP1HSP90B1 | |
| SCHEMBL31335842 | 0.84 | TRAP1 (0.44) | TRAP1HSP90AA1HSP90AB1HSP90B1 | |
| SCHEMBL31335595 | 0.84 | TRAP1 (0.44) | TRAP1HSP90AA1HSP90AB1HSP90B1 | |
| SCHEMBL31335551 | 0.80 | TRAP1 (0.49) | TRAP1HSP90AA1HSP90AB1HSP90B1 | |
| SCHEMBL31335739 | 0.78 | PDCD1 (0.34) | TRAP1HSP90B1 | |
| SCHEMBL31335749 | 0.76 | TRAP1 (0.44) | TRAP1HSP90AA1HSP90AB1HSP90B1 | |
| SCHEMBL31335762 | 0.74 | HSP90AA1 (0.55) | TRAP1HSP90AA1HSP90AB1HSP90B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4720038-A1 | (HETERO)ARYL-CARBONYL-HETEROBICYCLIC COMPOUNDS AS INHIBITORS OF PMS2 FOR CANCER AND DEGENERATIVE ILLNESSES | Neophore Limited (GB) | 2026-04-08 | — | — | EP | claimed |
| WO-2024246496-A1 | (HETERO)ARYL-CARBONYL-HETEROBICYCLIC COMPOUNDS AS INHIBITORS OF PMS2 FOR CANCER AND DEGENERATIVE ILLNESSES | Neophore Limited (GB) | 2024-12-05 | — | — | WO | claimed |
| EP-4720038-A1 | (HETERO)ARYL-CARBONYL-HETEROBICYCLIC COMPOUNDS AS INHIBITORS OF PMS2 FOR CANCER AND DEGENERATIVE ILLNESSES | Neophore Limited (GB) | 2026-04-08 | — | — | EP | disclosed |
| WO-2024246496-A1 | (HETERO)ARYL-CARBONYL-HETEROBICYCLIC COMPOUNDS AS INHIBITORS OF PMS2 FOR CANCER AND DEGENERATIVE ILLNESSES | Neophore Limited (GB) | 2024-12-05 | — | — | WO | disclosed |