Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 3/20 | 0.35 |
| ▸ | EGFR | P00533 | 6/20 | 0.33 |
| ▸ | TRAP1 | Q12931 | 6/20 | 0.33 |
| ▸ | HSP90B1 | P14625 | 4/20 | 0.33 |
| ▸ | BTK | Q06187 | 1/20 | 0.31 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.31 |
| ▸ | JAK3 | P52333 | 1/20 | 0.30 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | CCNK | O75909 | 1/20 | 0.30 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31335739 | 0.94 | PDCD1 (0.34) | SLC6A9EGFRTRAP1HSP90B1BTK | |
| SCHEMBL31335540 | 0.84 | TRAP1 (0.41) | TRAP1HSP90B1 | |
| SCHEMBL31335611 | 0.78 | TRAP1 (0.39) | EGFRTRAP1HSP90B1BTK | |
| SCHEMBL31335831 | 0.74 | TRAP1 (0.42) | SLC6A9TRAP1HSP90B1 | |
| SCHEMBL31335521 | 0.73 | TRAP1 (0.43) | EGFRTRAP1HSP90B1BTK | |
| SCHEMBL31335595 | 0.72 | TRAP1 (0.44) | TRAP1HSP90B1 | |
| SCHEMBL31335877 | 0.71 | SLC6A9 (0.40) | SLC6A9TRAP1HSP90B1POLBGAA | |
| SCHEMBL31335516 | 0.71 | BTK (0.44) | EGFRTRAP1HSP90B1BTKERBB2 | |
| SCHEMBL31335842 | 0.68 | TRAP1 (0.44) | TRAP1HSP90B1BTK | |
| SCHEMBL31336029 | 0.67 | HSP90B1 (0.44) | EGFRTRAP1HSP90B1BTKNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4720038-A1 | (HETERO)ARYL-CARBONYL-HETEROBICYCLIC COMPOUNDS AS INHIBITORS OF PMS2 FOR CANCER AND DEGENERATIVE ILLNESSES | Neophore Limited (GB) | 2026-04-08 | — | — | EP | disclosed |
| WO-2024246496-A1 | (HETERO)ARYL-CARBONYL-HETEROBICYCLIC COMPOUNDS AS INHIBITORS OF PMS2 FOR CANCER AND DEGENERATIVE ILLNESSES | Neophore Limited (GB) | 2024-12-05 | — | — | WO | disclosed |