Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRAP1 | Q12931 | 9/20 | 0.38 |
| ▸ | LYN | P07948 | 7/20 | 0.35 |
| ▸ | BTK | Q06187 | 7/20 | 0.35 |
| ▸ | SPR | P35270 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | HSP90B1 | P14625 | 5/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | EPHA8 | P29322 | 1/20 | 0.33 |
| ▸ | FRK | P42685 | 1/20 | 0.33 |
| ▸ | BLK | P51451 | 1/20 | 0.33 |
| ▸ | BMX | P51813 | 1/20 | 0.33 |
| ▸ | EPHB3 | P54753 | 1/20 | 0.33 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31335646 | 0.90 | SPR (0.43) | TRAP1LYNBTKSPRHSP90AA1 | |
| SCHEMBL31335822 | 0.88 | TRAP1 (0.36) | TRAP1LYNBTKSPRHSP90AA1 | |
| SCHEMBL31335962 | 0.86 | TRAP1 (0.41) | TRAP1SPRHSP90AA1HSP90AB1HSP90B1 | |
| SCHEMBL31335585 | 0.86 | SPR (0.36) | TRAP1LYNBTKSPRHSP90AA1 | |
| SCHEMBL31335603 | 0.84 | TRAP1 (0.45) | TRAP1HSP90AA1HSP90AB1HSP90B1 | |
| SCHEMBL31335881 | 0.84 | TRAP1 (0.49) | TRAP1HSP90AA1HSP90AB1HSP90B1 | |
| SCHEMBL25267660 | 0.84 | TRAP1 (0.36) | TRAP1LYNBTKSPRHSP90AA1 | |
| SCHEMBL30378186 | 0.84 | TRAP1 (0.36) | TRAP1LYNBTKSPRHSP90AA1 | |
| SCHEMBL31335814 | 0.84 | TRAP1 (0.38) | TRAP1LYNBTKEGFR | |
| SCHEMBL31335713 | 0.84 | TRAP1 (0.37) | TRAP1LYNBTKSPRHSP90B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4720038-A1 | (HETERO)ARYL-CARBONYL-HETEROBICYCLIC COMPOUNDS AS INHIBITORS OF PMS2 FOR CANCER AND DEGENERATIVE ILLNESSES | Neophore Limited (GB) | 2026-04-08 | — | — | EP | claimed |
| WO-2024246496-A1 | (HETERO)ARYL-CARBONYL-HETEROBICYCLIC COMPOUNDS AS INHIBITORS OF PMS2 FOR CANCER AND DEGENERATIVE ILLNESSES | Neophore Limited (GB) | 2024-12-05 | — | — | WO | claimed |
| EP-4720038-A1 | (HETERO)ARYL-CARBONYL-HETEROBICYCLIC COMPOUNDS AS INHIBITORS OF PMS2 FOR CANCER AND DEGENERATIVE ILLNESSES | Neophore Limited (GB) | 2026-04-08 | — | — | EP | disclosed |
| WO-2024246496-A1 | (HETERO)ARYL-CARBONYL-HETEROBICYCLIC COMPOUNDS AS INHIBITORS OF PMS2 FOR CANCER AND DEGENERATIVE ILLNESSES | Neophore Limited (GB) | 2024-12-05 | — | — | WO | disclosed |