Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRAP1 | Q12931 | 9/20 | 0.41 |
| ▸ | SPR | P35270 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 7/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 6/20 | 0.36 |
| ▸ | HSP90B1 | P14625 | 5/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31335781 | 0.87 | TRAP1 (0.39) | TRAP1SPRHSP90AA1HSP90AB1HSP90B1 | |
| SCHEMBL31335554 | 0.86 | TRAP1 (0.38) | TRAP1SPRHSP90AA1HSP90AB1HSP90B1 | |
| SCHEMBL31335618 | 0.84 | SPR (0.39) | TRAP1SPRHSP90AA1HSP90AB1HSP90B1 | |
| SCHEMBL31335788 | 0.83 | TRAP1 (0.48) | TRAP1HSP90AA1HSP90AB1HSP90B1 | |
| SCHEMBL25216773 | 0.83 | TRAP1 (0.38) | TRAP1SPRHSP90AA1HSP90AB1HSP90B1 | |
| SCHEMBL30970481 | 0.83 | TRAP1 (0.38) | TRAP1SPRHSP90AA1HSP90AB1HSP90B1 | |
| SCHEMBL31335555 | 0.82 | SPR (0.39) | TRAP1SPRHSP90AA1HSP90AB1HSP90B1 | |
| SCHEMBL31335751 | 0.81 | TRAP1 (0.40) | TRAP1SPRHSP90B1 | |
| SCHEMBL31335952 | 0.80 | TRAP1 (0.42) | TRAP1SPRHSP90AA1HSP90AB1HSP90B1 | |
| SCHEMBL31335943 | 0.77 | HSP90AA1 (0.44) | TRAP1HSP90AA1HSP90AB1HSP90B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4720038-A1 | (HETERO)ARYL-CARBONYL-HETEROBICYCLIC COMPOUNDS AS INHIBITORS OF PMS2 FOR CANCER AND DEGENERATIVE ILLNESSES | Neophore Limited (GB) | 2026-04-08 | — | — | EP | claimed |
| WO-2024246496-A1 | (HETERO)ARYL-CARBONYL-HETEROBICYCLIC COMPOUNDS AS INHIBITORS OF PMS2 FOR CANCER AND DEGENERATIVE ILLNESSES | Neophore Limited (GB) | 2024-12-05 | — | — | WO | claimed |
| EP-4720038-A1 | (HETERO)ARYL-CARBONYL-HETEROBICYCLIC COMPOUNDS AS INHIBITORS OF PMS2 FOR CANCER AND DEGENERATIVE ILLNESSES | Neophore Limited (GB) | 2026-04-08 | — | — | EP | disclosed |
| WO-2024246496-A1 | (HETERO)ARYL-CARBONYL-HETEROBICYCLIC COMPOUNDS AS INHIBITORS OF PMS2 FOR CANCER AND DEGENERATIVE ILLNESSES | Neophore Limited (GB) | 2024-12-05 | — | — | WO | disclosed |