Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 1/20 | 0.52 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.52 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.52 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.48 |
| ▸ | MEN1 | O00255 | 8/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 5/20 | 0.45 |
| ▸ | RAB9A | P51151 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1820368 | 0.85 | ABCC9 (0.62) | ABCC9ABCC8KCNJ11KCNJ8LMNA | |
| SCHEMBL3135074 | 0.83 | PTGS1 (0.48) | ABCC9ABCC8KCNJ11KCNJ8KMT2A | |
| SCHEMBL289758 | 0.81 | ABCC9 (0.53) | ABCC9ABCC8KCNJ11KCNJ8LMNA | |
| SCHEMBL13875633 | 0.80 | ABCC9 (0.58) | ABCC9ABCC8KCNJ11KCNJ8LMNA | |
| SCHEMBL1810895 | 0.78 | ABCC9 (0.57) | ABCC9ABCC8KCNJ11KCNJ8LMNA | |
| SCHEMBL1811552 | 0.78 | F2 (0.48) | ABCC9ABCC8KCNJ11KCNJ8LMNA | |
| SCHEMBL1767250 | 0.78 | ABCC9 (0.53) | ABCC9ABCC8KCNJ11KCNJ8LMNA | |
| SCHEMBL1766897 | 0.78 | ABCC9 (0.53) | ABCC9ABCC8KCNJ11KCNJ8LMNA | |
| SCHEMBL2113906 | 0.77 | ABCC9 (0.53) | ABCC9ABCC8KCNJ11KCNJ8LMNA | |
| SCHEMBL4187861 | 0.77 | ABCC9 (0.55) | ABCC9ABCC8KCNJ11KCNJ8LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8618173-B2 | Insecticidal compounds | SYNGENTA CROP PROTECTION, LLC (US) | 2013-12-31 | — | — | US | disclosed |
| WO-2013092942-A1 | USE OF AMINOBENZAMIDE DERIVATIVES FOR CONTROLLING ANIMAL PARASITES | SYNGENTA PARTICIPATIONS AG (CH) | 2013-06-27 | — | — | WO | disclosed |
| US-20100240712-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2010-09-23 | — | — | US | disclosed |
| US-20100240712-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2010-09-23 | — | — | US | disclosed |
| US-20100240712-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2010-09-23 | — | — | US | disclosed |
| EP-2203052-A2 | BISAMIDE DERIVATIVES AND THEIR USE AS INSECTICIDAL COMPOUNDS | Syngenta Participations AG (CH) | 2010-07-07 | — | — | EP | disclosed |
| WO-2009049845-A2 | BISAMIDE DERIVATIVES AND THEIR USE AS INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2009-04-23 | — | — | WO | disclosed |
| WO-2009049845-A2 | BISAMIDE DERIVATIVES AND THEIR USE AS INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2009-04-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100240712-A1 | INSECTICIDAL COMPOUNDS | CHRM1, CHRM2, ACHE | ABCC9 394/4885ABCC8 1511/4885KCNJ11 458/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.