Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPR | P35270 | 2/20 | 0.42 |
| ▸ | TRAP1 | Q12931 | 8/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 10/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 4/20 | 0.39 |
| ▸ | HSP90B1 | P14625 | 4/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.38 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31336056 | 0.89 | SPR (0.41) | SPRTRAP1HSP90AA1HSP90AB1HSP90B1 | |
| SCHEMBL31335642 | 0.88 | SPR (0.44) | SPRTRAP1HSP90AA1HSP90AB1HSP90B1 | |
| SCHEMBL4150793 | 0.81 | SPR (0.62) | SPRTRAP1HSP90AA1HSP90AB1HSP90B1 | |
| SCHEMBL31335933 | 0.77 | SPR (0.44) | SPRTRAP1HSP90AA1HSP90AB1HSP90B1 | |
| SCHEMBL31335566 | 0.76 | SPR (0.38) | SPRTRAP1HSP90AA1HSP90AB1HSP90B1 | |
| SCHEMBL31335926 | 0.76 | TRAP1 (0.37) | TRAP1HSP90AA1HSP90AB1HSP90B1TAS1R3 | |
| SCHEMBL31335618 | 0.74 | SPR (0.39) | SPRTRAP1HSP90AA1HSP90AB1HSP90B1 | |
| SCHEMBL31281835 | 0.73 | TRAP1 (0.45) | SPRTRAP1HSP90AA1HSP90AB1HSP90B1 | |
| SCHEMBL31335718 | 0.72 | SPR (0.54) | SPRTRAP1HSP90AA1HSP90AB1HSP90B1 | |
| SCHEMBL31282296 | 0.72 | TRAP1 (0.42) | SPRTRAP1HSP90AA1HSP90AB1HSP90B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4720038-A1 | (HETERO)ARYL-CARBONYL-HETEROBICYCLIC COMPOUNDS AS INHIBITORS OF PMS2 FOR CANCER AND DEGENERATIVE ILLNESSES | Neophore Limited (GB) | 2026-04-08 | — | — | EP | disclosed |
| WO-2024246496-A1 | (HETERO)ARYL-CARBONYL-HETEROBICYCLIC COMPOUNDS AS INHIBITORS OF PMS2 FOR CANCER AND DEGENERATIVE ILLNESSES | Neophore Limited (GB) | 2024-12-05 | — | — | WO | disclosed |