Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPR | P35270 | 2/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 8/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 3/20 | 0.41 |
| ▸ | TRAP1 | Q12931 | 10/20 | 0.40 |
| ▸ | HSP90B1 | P14625 | 4/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31335771 | 0.89 | SPR (0.42) | SPRHSP90AA1HSP90AB1TRAP1HSP90B1 | |
| SCHEMBL31335933 | 0.89 | SPR (0.44) | SPRHSP90AA1HSP90AB1TRAP1HSP90B1 | |
| SCHEMBL31335642 | 0.77 | SPR (0.44) | SPRHSP90AA1HSP90AB1TRAP1HSP90B1 | |
| SCHEMBL31335555 | 0.75 | SPR (0.39) | SPRHSP90AA1HSP90AB1TRAP1HSP90B1 | |
| SCHEMBL31335765 | 0.73 | SPR (0.34) | SPRHSP90AA1HSP90AB1TRAP1HSP90B1 | |
| SCHEMBL31335537 | 0.73 | SPR (0.36) | SPRHSP90AA1HSP90AB1TRAP1HSP90B1 | |
| SCHEMBL31335718 | 0.71 | SPR (0.54) | SPRHSP90AA1HSP90AB1TRAP1HSP90B1 | |
| SCHEMBL31335926 | 0.71 | TRAP1 (0.37) | HSP90AA1HSP90AB1TRAP1HSP90B1 | |
| SCHEMBL31335935 | 0.68 | DDB1 (0.49) | DPP8DPP9DPP7 | |
| SCHEMBL4150793 | 0.68 | SPR (0.62) | SPRHSP90AA1HSP90AB1TRAP1HSP90B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4720038-A1 | (HETERO)ARYL-CARBONYL-HETEROBICYCLIC COMPOUNDS AS INHIBITORS OF PMS2 FOR CANCER AND DEGENERATIVE ILLNESSES | Neophore Limited (GB) | 2026-04-08 | — | — | EP | disclosed |
| WO-2024246496-A1 | (HETERO)ARYL-CARBONYL-HETEROBICYCLIC COMPOUNDS AS INHIBITORS OF PMS2 FOR CANCER AND DEGENERATIVE ILLNESSES | Neophore Limited (GB) | 2024-12-05 | — | — | WO | disclosed |