Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.53 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.53 |
| ▸ | FABP3 | P05413 | 1/20 | 0.47 |
| ▸ | FABP4 | P15090 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | HPGD | P15428 | 5/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.44 |
| ▸ | GRM1 | Q13255 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.44 |
| ▸ | SELL | P14151 | 2/20 | 0.42 |
| ▸ | SELP | P16109 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4869322 | 1.00 | GABRA1 (0.53) | GABRA1GABRB2FABP3FABP4ALDH1A1 | |
| SCHEMBL212716 | 0.82 | FABP3 (0.60) | GABRA1GABRB2FABP3FABP4ALDH1A1 | |
| SCHEMBL29593831 | 0.82 | FABP3 (0.60) | GABRA1GABRB2FABP3FABP4ALDH1A1 | |
| SCHEMBL15524641 | 0.82 | HDAC4 (0.42) | ALDH1A1HSD17B10KDM4EHPGDTDP1 | |
| SCHEMBL11797932 | 0.81 | FABP3 (0.58) | GABRA1GABRB2FABP3FABP4ALDH1A1 | |
| SCHEMBL10618114 | 0.81 | FABP3 (0.58) | GABRA1GABRB2FABP3FABP4ALDH1A1 | |
| SCHEMBL11794494 | 0.81 | FABP3 (0.58) | GABRA1GABRB2FABP3FABP4ALDH1A1 | |
| SCHEMBL11783529 | 0.81 | FABP3 (0.58) | GABRA1GABRB2FABP3FABP4ALDH1A1 | |
| Water SCHEMBL5706121 | 0.81 | FABP3 (0.58) | GABRA1GABRB2FABP3FABP4ALDH1A1 | |
| SCHEMBL6910525 | 0.81 | FABP3 (0.58) | GABRA1GABRB2FABP3FABP4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4720038-A1 | (HETERO)ARYL-CARBONYL-HETEROBICYCLIC COMPOUNDS AS INHIBITORS OF PMS2 FOR CANCER AND DEGENERATIVE ILLNESSES | Neophore Limited (GB) | 2026-04-08 | — | — | EP | disclosed |
| WO-2024246496-A1 | (HETERO)ARYL-CARBONYL-HETEROBICYCLIC COMPOUNDS AS INHIBITORS OF PMS2 FOR CANCER AND DEGENERATIVE ILLNESSES | Neophore Limited (GB) | 2024-12-05 | — | — | WO | disclosed |