Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR4 | P22455 | 4/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 8/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.36 |
| ▸ | HSP90B1 | P14625 | 4/20 | 0.35 |
| ▸ | SPR | P35270 | 1/20 | 0.34 |
| ▸ | KRAS | P01116 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31335544 | 0.84 | FGFR1 (0.38) | FGFR4FGFR1SPRKRASMEN1 | |
| SCHEMBL31335484 | 0.83 | HSP90AA1 (0.51) | HSP90AA1HSP90B1 | |
| SCHEMBL31335613 | 0.82 | FGFR1 (0.38) | FGFR4FGFR1HSP90AA1HSP90AB1HSP90B1 | |
| SCHEMBL31335590 | 0.81 | FGFR1 (0.41) | FGFR4FGFR1HSP90AA1HSP90AB1HSP90B1 | |
| SCHEMBL31335632 | 0.81 | MAPT (0.39) | HSP90B1KRASMEN1KMT2A | |
| SCHEMBL31335742 | 0.81 | SPR (0.39) | FGFR4FGFR1SPRKRASMEN1 | |
| SCHEMBL31335751 | 0.78 | TRAP1 (0.40) | FGFR4FGFR1HSP90B1SPRKRAS | |
| SCHEMBL31335678 | 0.78 | FGFR4 (0.39) | FGFR4HSP90AA1HSP90AB1HSP90B1KRAS | |
| SCHEMBL31335681 | 0.76 | HSP90AA1 (0.35) | HSP90AA1HSP90AB1HSP90B1SPRMEN1 | |
| SCHEMBL31335640 | 0.76 | FGFR4 (0.35) | FGFR4FGFR1HSP90B1SPRKRAS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4720038-A1 | (HETERO)ARYL-CARBONYL-HETEROBICYCLIC COMPOUNDS AS INHIBITORS OF PMS2 FOR CANCER AND DEGENERATIVE ILLNESSES | Neophore Limited (GB) | 2026-04-08 | — | — | EP | claimed |
| WO-2024246496-A1 | (HETERO)ARYL-CARBONYL-HETEROBICYCLIC COMPOUNDS AS INHIBITORS OF PMS2 FOR CANCER AND DEGENERATIVE ILLNESSES | Neophore Limited (GB) | 2024-12-05 | — | — | WO | claimed |
| EP-4720038-A1 | (HETERO)ARYL-CARBONYL-HETEROBICYCLIC COMPOUNDS AS INHIBITORS OF PMS2 FOR CANCER AND DEGENERATIVE ILLNESSES | Neophore Limited (GB) | 2026-04-08 | — | — | EP | disclosed |
| WO-2024246496-A1 | (HETERO)ARYL-CARBONYL-HETEROBICYCLIC COMPOUNDS AS INHIBITORS OF PMS2 FOR CANCER AND DEGENERATIVE ILLNESSES | Neophore Limited (GB) | 2024-12-05 | — | — | WO | disclosed |