SCHEMBL3133578

SCHEMBL3133578

CC(=O)C(C)C(=O)C(=O)O

nearest known ligand 0.42

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
FFAR3 O14843 1/20 0.35
LCK P06239 1/20 0.35
FYN P06241 1/20 0.35
TP53 P04637 1/20 0.35
ALDH1A1 P00352 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9127407 0.97 TP53 (0.33) FFAR3LCKFYNTP53
SCHEMBL9243318 0.83 TP53 (0.41) FFAR3LCKFYNTP53
SCHEMBL367536 0.78 TP53 (0.44) TP53ALDH1A1TSHR
SCHEMBL1331725 0.78 TP53 (0.44) TP53ALDH1A1TSHR
SCHEMBL93292 0.75
SCHEMBL5386710 0.73
SCHEMBL79779 0.73
SCHEMBL16593537 0.73 TSHR (0.33) TSHR
SCHEMBL4816037 0.73 TDP1 (0.38) ALDH1A1TDP1TSHR
Oxalic Acid SCHEMBL29212905 0.73 TP53 (0.33) FFAR3LCKFYNTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2776162-B1 MOISTURE CURABLE ORGANOPOLYSILOXANE COMPOSITION MOMENTIVE PERFORMANCE MAT INC (US) 2017-01-04 EP claimed
US-9394443-B2 Moisture curable organopolysiloxane composition MOMENTIVE PERFORMANCE MATERIALS, INC. (US) 2016-07-19 US claimed
US-20140343202-A1 MOISTURE CURABLE ORGANOPOLYSILOXANE COMPOSITION MOMENTIVE PERFORMANCE MATERIALS INC. 2014-11-20 US claimed
EP-2776162-A1 MOISTURE CURABLE ORGANOPOLYSILOXANE COMPOSITION Momentive Performance Materials Inc. (US) 2014-09-17 EP claimed
WO-2013070227-A1 MOISTURE CURABLE COMPOSITION OF A POLYMER HAVING SILYL GROUPS MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2013-05-16 WO claimed
WO-2013071078-A1 MOISTURE CURABLE ORGANOPOLYSILOXANE COMPOSITION MOMENTIVE PERFORMANCE MATERIALS, INC. (US) 2013-05-16 WO claimed
EP-0234065-B1 PROCESS FOR THE TREATMENT OF AN AQUEOUS SUGAR SOLUTION IN ORDER TO ISOLATE AND SEPARATE THE SACCHARIDES HAVING A CETONIC FUNCTION INSTITUT NATIONAL POLYTECHNIQUE DE TOULOUSE (I.N.P.T.) (FR) 1989-11-08 EP claimed
US-20230407046-A1 METAL-CONTAINING ADDITIVE, CROSSLINKABLE POLYMER COMPOSITION, CROSSLINKED POLYMER MATERIAL, METAL MEMBER, AND WIRE HARNESS AUTONETWORKS TECHNOLOGIES, LTD. (JP) 2023-12-21 US disclosed
US-20230399525-A1 CROSSLINKABLE POLYMER COMPOSITION, CROSSLINKED POLYMER MATERIAL, METAL MEMBER, AND WIRING HARNESS AUTONETWORKS TECHNOLOGIES, LTD. (JP) 2023-12-14 US disclosed
US-20230265263-A1 METAL-CROSSLINKABLE POLYMER COMPOSITION, METAL-CROSSLINKED POLYMERIC MATERIAL, METAL COMPONENT, AND WIRING HARNESS AUTONETWORKS TECHNOLOGIES, LTD. (JP) 2023-08-24 US disclosed
EP-2776162-B1 MOISTURE CURABLE ORGANOPOLYSILOXANE COMPOSITION MOMENTIVE PERFORMANCE MAT INC (US) 2017-01-04 EP disclosed
US-9394443-B2 Moisture curable organopolysiloxane composition MOMENTIVE PERFORMANCE MATERIALS, INC. (US) 2016-07-19 US disclosed
EP-2714030-B1 FE(III) 2,4-DIOXO-1-CARBONYL COMPLEXES FOR USE IN THE TREATMENT AND THE PROPHYLAXIS OF IRON DEFICIENCY SYMPTOMS AND IRON DEFICIENCY ANAEMIAS VIFOR INT AG (CH) 2015-08-12 EP disclosed
US-20020052535-A1 Method of alkylating aromatic hydrocarbon NIPPON MITSUBISHI OIL CORPORATION (JP) 2002-05-02 US disclosed
US-6372744-B1 PROTEASE OR KINASE INHIBITORS MOLECUMETICS LTD. 2002-04-16 US disclosed
EP-1078913-A2 Process for the preparation of diesters of (meth)acrylic acid RÖHM GMBH (DE) 2001-02-28 EP disclosed
US-6117896-A Methods for regulating transcription factors MOLECUMETICS LTD. (US) 2000-09-12 US disclosed
EP-0915700-A1 USE OF BETA-SHEET MIMETICS AS PROTEASE AND KINASE INHIBITORS AND AS INHIBITORS OF TRANSCRIPTION FACTORS MOLECUMETICS, LTD. (US) 1999-05-19 EP disclosed
WO-1998005333-A1 USE OF BETA-SHEET MIMETICS AS PROTEASE AND KINASE INHIBITORS AND AS INHIBITORS OF TRANSCRIPTION FACTORS MOLECUMETICS LTD. (US) 1998-02-12 WO disclosed
US-4017552-A Bicyclo-[3'3'0]-octa-2-ene formed by isomerizing 1,5-cyclooctadiene THE GOODYEAR TIRE & RUBBER COMPANY (US) 1977-04-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140343202-A1 MOISTURE CURABLE ORGANOPOLYSILOXANE COMPOSITION TST, SMCHD1, SBDS FFAR3 3393/4885LCK 3427/4885FYN 3610/4885
US-20020052535-A1 Method of alkylating aromatic hydrocarbon AHR, ALKBH3, ALKBH2 FFAR3 1937/4885LCK 629/4885FYN 2230/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.