Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRAP1 | Q12931 | 3/20 | 0.34 |
| ▸ | HSP90B1 | P14625 | 2/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.33 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TOP1 | P11387 | 2/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31335926 | 0.89 | TRAP1 (0.37) | TRAP1HSP90B1TDP1L3MBTL1POLB | |
| SCHEMBL31336035 | 0.85 | TRAP1 (0.36) | TRAP1HSP90B1TDP1L3MBTL1POLB | |
| SCHEMBL31335727 | 0.74 | POLB (0.35) | POLBKDM4E | |
| SCHEMBL31335899 | 0.74 | BTK (0.33) | TRAP1HSP90B1TDP1L3MBTL1SLC6A9 | |
| SCHEMBL31013975 | 0.72 | DDB1 (0.46) | PTGER4RXFP1KDM4E | |
| SCHEMBL25601416 | 0.67 | TRAP1 (0.38) | TRAP1HSP90B1MEN1KMT2ASLC6A9 | |
| SCHEMBL31013748 | 0.66 | RXFP1 (0.37) | PTGER4PRMT5WDR77ALDH1A1MCL1 | |
| SCHEMBL24914227 | 0.66 | PTGDR2 (0.40) | PRMT5WDR77L3MBTL1KDM4EKMT2A | |
| SCHEMBL30155768 | 0.66 | PTGDR2 (0.40) | PRMT5WDR77L3MBTL1KDM4EKMT2A | |
| SCHEMBL31013929 | 0.66 | ESR2 (0.46) | PRMT5WDR77HPGDTMEM97SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4720038-A1 | (HETERO)ARYL-CARBONYL-HETEROBICYCLIC COMPOUNDS AS INHIBITORS OF PMS2 FOR CANCER AND DEGENERATIVE ILLNESSES | Neophore Limited (GB) | 2026-04-08 | — | — | EP | disclosed |
| WO-2024246496-A1 | (HETERO)ARYL-CARBONYL-HETEROBICYCLIC COMPOUNDS AS INHIBITORS OF PMS2 FOR CANCER AND DEGENERATIVE ILLNESSES | Neophore Limited (GB) | 2024-12-05 | — | — | WO | disclosed |