Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRAP1 | Q12931 | 5/20 | 0.36 |
| ▸ | HSP90B1 | P14625 | 2/20 | 0.36 |
| ▸ | SLC6A9 | P48067 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TOP1 | P11387 | 2/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.34 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31335926 | 0.89 | TRAP1 (0.37) | TRAP1HSP90B1SLC6A9POLBTDP1 | |
| SCHEMBL31335727 | 0.86 | POLB (0.35) | POLB | |
| SCHEMBL31335875 | 0.85 | TRAP1 (0.34) | TRAP1HSP90B1SLC6A9POLBTDP1 | |
| SCHEMBL25601416 | 0.78 | TRAP1 (0.38) | TRAP1HSP90B1SLC6A9TAS1R3TAS1R1 | |
| SCHEMBL31335899 | 0.77 | BTK (0.33) | TRAP1HSP90B1SLC6A9TDP1L3MBTL1 | |
| SCHEMBL25601427 | 0.77 | TRAP1 (0.42) | TRAP1HSP90B1 | |
| SCHEMBL31282296 | 0.77 | TRAP1 (0.42) | TRAP1HSP90B1 | |
| SCHEMBL31281835 | 0.74 | TRAP1 (0.45) | TRAP1HSP90B1 | |
| SCHEMBL31335642 | 0.74 | SPR (0.44) | TRAP1HSP90B1TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL31282001 | 0.73 | TRAP1 (0.36) | TRAP1HSP90B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4720038-A1 | (HETERO)ARYL-CARBONYL-HETEROBICYCLIC COMPOUNDS AS INHIBITORS OF PMS2 FOR CANCER AND DEGENERATIVE ILLNESSES | Neophore Limited (GB) | 2026-04-08 | — | — | EP | disclosed |
| WO-2024246496-A1 | (HETERO)ARYL-CARBONYL-HETEROBICYCLIC COMPOUNDS AS INHIBITORS OF PMS2 FOR CANCER AND DEGENERATIVE ILLNESSES | Neophore Limited (GB) | 2024-12-05 | — | — | WO | disclosed |