Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRAP1 | Q12931 | 6/20 | 0.38 |
| ▸ | HSP90B1 | P14625 | 3/20 | 0.38 |
| ▸ | NAMPT | P43490 | 3/20 | 0.35 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.33 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25601427 | 0.82 | TRAP1 (0.42) | TRAP1HSP90B1NAMPT | |
| SCHEMBL31282296 | 0.82 | TRAP1 (0.42) | TRAP1HSP90B1NAMPT | |
| SCHEMBL25250913 | 0.82 | KMT2A (0.40) | TRAP1HSP90B1MEN1KMT2ASLC6A9 | |
| SCHEMBL31336035 | 0.78 | TRAP1 (0.36) | TRAP1HSP90B1ABHD6SLC6A9TAS1R3 | |
| SCHEMBL30970484 | 0.74 | TRAP1 (0.32) | TRAP1HSP90B1MEN1KMT2ANPSR1 | |
| SCHEMBL31281835 | 0.72 | TRAP1 (0.45) | TRAP1HSP90B1NAMPT | |
| SCHEMBL31335642 | 0.72 | SPR (0.44) | TRAP1HSP90B1TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL31335970 | 0.71 | TRAP1 (0.46) | TRAP1HSP90B1NAMPTLMNA | |
| SCHEMBL31335915 | 0.70 | TRAP1 (0.37) | TRAP1HSP90B1ABHD6NPSR1SLC6A9 | |
| SCHEMBL25212825 | 0.70 | KMT2A (0.41) | TRAP1HSP90B1MEN1KMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023094834-A1 | ISOINDOLINES AS PMS2 INHIBITORS | Neophore Limited (GB) | 2023-06-01 | — | — | WO | disclosed |