Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MELK | Q14680 | 2/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 6/20 | 0.48 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.48 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.47 |
| ▸ | ITGA2 | P17301 | 2/20 | 0.45 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | BTK | Q06187 | 1/20 | 0.42 |
| ▸ | ITK | Q08881 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | PRKG1 | Q13976 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL31335956 | 0.99 | ITGB3 (0.50) | MELKITGB3ITGA2BSLC2A1ITGA2 | |
| SCHEMBL31336033 | 0.78 | BTK (0.44) | BTK | |
| Hydrochloric Acid SCHEMBL31335684 | 0.77 | BTK (0.44) | BTK | |
| SCHEMBL31336083 | 0.76 | KDM4E (0.46) | ITK | |
| SCHEMBL3891388 | 0.76 | MELK (0.63) | MELKITGB3ITGA2BSLC2A1ITGA2 | |
| SCHEMBL31174281 | 0.76 | MELK (0.63) | MELKITGB3ITGA2BSLC2A1ITGA2 | |
| SCHEMBL1045965 | 0.74 | MELK (0.64) | MELKITGB3ITGA2BSLC2A1ITGA2 | |
| SCHEMBL8117385 | 0.73 | MELK (0.63) | MELKITGB3ITGA2BSLC2A1ITGA2 | |
| SCHEMBL19241572 | 0.72 | NAMPT (0.53) | — | |
| Hydrochloric Acid SCHEMBL31335969 | 0.72 | MELK (0.55) | MELKITGB3ITGA2BSLC2A1ITGA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4720038-A1 | (HETERO)ARYL-CARBONYL-HETEROBICYCLIC COMPOUNDS AS INHIBITORS OF PMS2 FOR CANCER AND DEGENERATIVE ILLNESSES | Neophore Limited (GB) | 2026-04-08 | — | — | EP | disclosed |
| WO-2024246496-A1 | (HETERO)ARYL-CARBONYL-HETEROBICYCLIC COMPOUNDS AS INHIBITORS OF PMS2 FOR CANCER AND DEGENERATIVE ILLNESSES | Neophore Limited (GB) | 2024-12-05 | — | — | WO | disclosed |