Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF4A3 | P38919 | 1/20 | 0.47 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.44 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.41 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.41 |
| ▸ | ALB | P02768 | 2/20 | 0.40 |
| ▸ | FABP3 | P05413 | 1/20 | 0.40 |
| ▸ | FABP4 | P15090 | 1/20 | 0.40 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.39 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.39 |
| ▸ | BCL2 | P10415 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.39 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL71656 | 0.85 | MEN1 (0.46) | EIF4A3GRM1FABP3FABP4HSP90AA1 | |
| SCHEMBL29924059 | 0.82 | HSP90AA1 (0.53) | GRM1FABP3FABP4CSNK2A1HSP90AA1 | |
| SCHEMBL18677495 | 0.82 | HSP90AA1 (0.53) | GRM1FABP3FABP4CSNK2A1HSP90AA1 | |
| SCHEMBL16939392 | 0.81 | EIF4A3 (0.50) | EIF4A3IKBKETBK1ALBFABP3 | |
| SCHEMBL31335818 | 0.81 | CA12 (0.46) | EIF4A3HSP90AA1HSP90AB1CA1CA2 | |
| SCHEMBL9252960 | 0.79 | GRM1 (0.57) | GRM1FABP3FABP4CSNK2A1HSP90AA1 | |
| SCHEMBL15631290 | 0.78 | ADRA1A (0.54) | EIF4A3MAPTNPSR1CA1CA2 | |
| SCHEMBL2551682 | 0.78 | CA1 (0.48) | ALBCSNK2A1MEN1KMT2AMAPT | |
| SCHEMBL18671875 | 0.76 | EIF4A3 (0.50) | EIF4A3IKBKETBK1FABP3FABP4 | |
| SCHEMBL5377474 | 0.76 | GABRA1 (0.45) | EIF4A3MAPTNPSR1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4720038-A1 | (HETERO)ARYL-CARBONYL-HETEROBICYCLIC COMPOUNDS AS INHIBITORS OF PMS2 FOR CANCER AND DEGENERATIVE ILLNESSES | Neophore Limited (GB) | 2026-04-08 | — | — | EP | disclosed |
| WO-2024246496-A1 | (HETERO)ARYL-CARBONYL-HETEROBICYCLIC COMPOUNDS AS INHIBITORS OF PMS2 FOR CANCER AND DEGENERATIVE ILLNESSES | Neophore Limited (GB) | 2024-12-05 | — | — | WO | disclosed |