SCHEMBL3133633

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL167426	0.86	CFTR (0.71)	CFTRKDM4EGAAHSD17B10ALDH1A1
	SCHEMBL5354905	0.84	CFTR (0.51)	CFTRKDM4EGAAHSD17B10ALDH1A1
	SCHEMBL18512401	0.81	CFTR (0.50)	CFTRKDM4EGAAHSD17B10ALDH1A1
	SCHEMBL5355523	0.81	KDM4E (0.41)	CFTRKDM4EHSD17B10ALDH1A1HPGD
	SCHEMBL3146241	0.81	RXRB (0.41)	CFTRKDM4EHSD17B10ALDH1A1HPGD
	SCHEMBL2892428	0.81	CFTR (0.50)	CFTRKDM4EGAAHSD17B10ALDH1A1
	SCHEMBL3138225	0.81	RXRB (0.57)	KDM4EHSD17B10ALDH1A1HPGDNOTUM
	SCHEMBL19970602	0.81	CFTR (0.59)	CFTRKDM4EGAAHSD17B10ALDH1A1
	SCHEMBL5358259	0.80	CFTR (0.48)	CFTRKDM4EGAAHSD17B10ALDH1A1
	SCHEMBL2270134	0.80	CFTR (0.57)	CFTRKDM4EGAAALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.