SCHEMBL31336633

SCHEMBL31336633

[2H]C([2H])([2H])n1nc(C=O)c(-c2ncc(F)cn2)c1C

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
KDM4C Q9H3R0 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28927799 0.90 HCRTR1 (0.33) KDM4C
SCHEMBL31336916 0.86
SCHEMBL31336634 0.83 PDE2A (0.35) KDM4C
SCHEMBL31336696 0.76 HCRTR1 (0.36)
SCHEMBL31336880 0.72 PDE2A (0.39) KDM4C
SCHEMBL28645151 0.72 KDM4C (0.37) KDM4C
SCHEMBL31336773 0.70 HCRTR1 (0.37)
SCHEMBL31336944 0.66 CYP11B2 (0.38)
SCHEMBL31336831 0.65 CCR1 (0.33) KDM4C
SCHEMBL31336853 0.65 THRB (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4688154-A1 MORPHOLINE OREXIN RECEPTOR ANTAGONISTS BIAL - Portela & Ca., S.A. (PT) 2026-02-11 EP disclosed
WO-2025023851-A1 MORPHOLINE OREXIN RECEPTOR ANTAGONISTS BIAL - PORTELA & CA., S.A. (PT) 2025-01-30 WO disclosed