Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28927799 | 0.82 | HCRTR1 (0.33) | KDM4C | |
| SCHEMBL31336916 | 0.72 | — | — | |
| SCHEMBL31336633 | 0.72 | KDM4C (0.30) | KDM4C | |
| SCHEMBL19207132 | 0.71 | MYC (0.41) | KDM4CNPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL31336831 | 0.71 | CCR1 (0.33) | KDM4CNPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL31336880 | 0.70 | PDE2A (0.39) | KDM4CNPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL31336809 | 0.68 | POLB (0.40) | NPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL20135919 | 0.68 | NOS2 (0.35) | ALDH1A1 | |
| SCHEMBL28648049 | 0.67 | BRD4 (0.40) | BRD4 | |
| SCHEMBL31336944 | 0.66 | CYP11B2 (0.38) | BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109219606-B | Halogen substituted piperidines as orexin receptor modulators | 阿斯利康(瑞典)有限公司 | 2021-10-01 | — | — | CN | disclosed |