SCHEMBL3133672

SCHEMBL3133672

CC(C)(C)C1CCC(c2ccc(O)cc2)CC1

nearest known ligand 0.62

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 19/20 0.62
ESR1 P03372 7/20 0.53
CYP3A4 P08684 2/20 0.53
CYP2C9 P11712 2/20 0.53
CYP2D6 P10635 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4147450 0.88 ESR2 (0.62) ESR2ESR1CYP3A4CYP2C9CYP2D6
SCHEMBL1986271 0.82 ESR2 (0.81) ESR2ESR1CYP3A4CYP2C9CYP2D6
SCHEMBL3809909 0.82 ESR2 (0.81) ESR2ESR1CYP3A4CYP2C9CYP2D6
SCHEMBL1865798 0.82 ESR2 (0.81) ESR2ESR1CYP3A4CYP2C9CYP2D6
SCHEMBL3811445 0.82 ESR2 (0.81) ESR2ESR1CYP3A4CYP2C9CYP2D6
SCHEMBL25072706 0.80 ALDH1A1 (0.41) ESR2CYP2C9
SCHEMBL4397354 0.80 ESR2 (0.38) ESR2ESR1CYP3A4CYP2C9
SCHEMBL28106275 0.80 SLC18A3 (0.40) ESR2CYP2C9
SCHEMBL12000552 0.80 DRD2 (0.47) ESR2CYP2C9
SCHEMBL31574441 0.78 ESR2 (0.74) ESR2ESR1CYP3A4CYP2C9CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117980406-A Polycarbonate resin composition 三菱工程塑料株式会社 2024-05-03 CN disclosed
CN-117881743-A Resin composition and molded article 三菱工程塑料株式会社 2024-04-12 CN disclosed
CN-117062875-A Polycarbonate resin composition 三菱工程塑料株式会社 2023-11-14 CN disclosed
CN-114174378-B Polycarbonate resin 三菱瓦斯化学株式会社 2023-07-04 CN disclosed
CN-114466896-B Polycarbonate resin composition 三菱工程塑料株式会社 2023-05-30 CN disclosed
CN-116082814-A High-light-transmittance low-fiber-floating glass fiber reinforced PC composition and preparation method thereof 上海锦湖日丽塑料有限公司 2023-05-09 CN disclosed
CN-111936578-B Polycarbonate resin composition 三菱工程塑料株式会社 2023-03-10 CN disclosed
CN-111201281-B Polycarbonate resin composition 三菱工程塑料株式会社 2022-09-09 CN disclosed
CN-114466896-A Polycarbonate resin composition 三菱工程塑料株式会社 2022-05-10 CN disclosed
CN-110753714-B Aromatic polycarbonate resin, process for producing the same, and aromatic dihydroxy compound 三菱化学株式会社 2022-04-29 CN disclosed
CN-104447792-A Substituted dihydro and tetrahydro oxazolopyrimidinones, preparation and use thereof SANOFI AVENTIS 2015-03-25 CN disclosed
US-8642603-B2 Substituted dihydro and tetrahydro oxazolopyrimidinones, preparation and use thereof SANOFI (FR) 2014-02-04 US disclosed
US-20100075994-A1 SUBSTITUTED DIHYDRO AND TETRAHYDRO OXAZOLOPYRIMIDINONES, PREPARATION AND USE THEREOF SANOFI-AVENTIS (FR) 2010-03-25 US disclosed
CN-101675060-A Substituted dihydro and tetrahydro oxazolopyrimidinones, their preparation and use SANOFI AVENTIS 2010-03-17 CN disclosed
EP-2137193-A2 SUBSTITUTED DIHYDRO AND TETRAHYDRO OXAZOLOPYRIMIDINONES, PREPARATION AND USE THEREOF Sanofi-Aventis (FR) 2009-12-30 EP disclosed
US-20090306376-A1 OPTICAL RECORDING MEDIUM AND COMPOUND USED FOR THE SAME MITSUI CHEMICALS, INC. (JP) 2009-12-10 US disclosed
WO-2008112483-A2 SUBSTITUTED DIHYDRO AND TETRAHYDRO OXAZOLOPYRIMIDINONES, PREPARATION AND USE THEREOF SANOFI-AVENTIS (FR) 2008-09-18 WO disclosed
US-20070054084-A1 Optical recording medium and compound used for the same MITSUI CHEMICALS, INC. (JP) 2007-03-08 US disclosed
EP-1672626-A1 OPTICAL RECORDING MEDIUM AND COMPOUND USED IN THE OPTICAL RECORDING MEDIUM Mitsui Chemicals, Inc. (JP) 2006-06-21 EP disclosed
EP-0990633-A1 PROCESSES FOR PRODUCING p-SUBSTITUTED PHENOLS CHISSO CORPORATION (JP) 2000-04-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090306376-A1 OPTICAL RECORDING MEDIUM AND COMPOUND USED FOR THE SAME CACNA1B, KCNN4, KCNN2 ESR2 2909/4885ESR1 4389/4885CYP3A4 2777/4885
US-20100075994-A1 SUBSTITUTED DIHYDRO AND TETRAHYDRO OXAZOLOPYRIMIDINONES, PREPARATION AND USE THEREOF GRM2, GRM1, GRIN2C ESR2 491/4885ESR1 699/4885CYP3A4 1201/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.