Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 10/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 10/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 10/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 10/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 10/20 | 0.35 |
| ▸ | GABRA6 | Q16445 | 10/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 6/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.35 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31336884 | 0.81 | GABRA1 (0.32) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL3798240 | 0.80 | PDE3B (0.39) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL25412983 | 0.80 | GABRA1 (0.34) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL30515595 | 0.79 | GABRA1 (0.35) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL28480405 | 0.77 | — | — | |
| SCHEMBL30793876 | 0.75 | NR1H2 (0.42) | MEN1KMT2AMAPK1 | |
| SCHEMBL31336736 | 0.74 | THRB (0.33) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL30793168 | 0.72 | ADORA1 (0.42) | GABRG2GABRB3GABRA5MEN1KMT2A | |
| SCHEMBL28643148 | 0.72 | KMT2A (0.32) | KMT2A | |
| SCHEMBL30752612 | 0.71 | NR1H2 (0.46) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4688154-A1 | MORPHOLINE OREXIN RECEPTOR ANTAGONISTS | BIAL - Portela & Ca., S.A. (PT) | 2026-02-11 | — | — | EP | disclosed |
| EP-4688155-A1 | MORPHOLINE OREXIN RECEPTOR ANTAGONISTS | Bial-Portela & CA, S.A. (PT) | 2026-02-11 | — | — | EP | disclosed |
| WO-2025023851-A1 | MORPHOLINE OREXIN RECEPTOR ANTAGONISTS | BIAL - PORTELA & CA., S.A. (PT) | 2025-01-30 | — | — | WO | disclosed |
| WO-2025023852-A1 | MORPHOLINE OREXIN RECEPTOR ANTAGONISTS | BIAL - PORTELA & CA., S.A. (PT) | 2025-01-30 | — | — | WO | disclosed |