Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.35 |
| ▸ | CCR1 | P32246 | 3/20 | 0.34 |
| ▸ | CCR8 | P51685 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | PDE2A | O00408 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31336815 | 0.77 | NOS3 (0.41) | CCR1CCR8CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL31336616 | 0.75 | TDP1 (0.38) | CYP1A2CYP3A4ALDH1A1MAPTKMT2A | |
| SCHEMBL3894660 | 0.73 | CYP19A1 (0.35) | CYP19A1CCR1CCR8CYP1A2CYP3A4 | |
| SCHEMBL31336841 | 0.73 | CCR1 (0.35) | CCR1CCR8CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL16385309 | 0.72 | ALDH1A1 (0.48) | CYP19A1CCR1CCR8CYP1A2CYP3A4 | |
| SCHEMBL31336812 | 0.72 | ALOX15 (0.42) | ALDH1A1MAPTATMHTTKDM4E | |
| SCHEMBL22332415 | 0.69 | KDM4E (0.37) | CYP1A2CYP3A4CYP2C19ALDH1A1MAPT | |
| SCHEMBL16231621 | 0.68 | KDM4E (0.40) | CYP1A2CYP3A4CYP2C19MEN1ALDH1A1 | |
| SCHEMBL20743957 | 0.67 | KDM1A (0.33) | CYP19A1KDM1AMKNK1MKNK2 | |
| SCHEMBL30961368 | 0.65 | CYP19A1 (0.32) | CYP19A1CCR1CCR8CYP3A4KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4688154-A1 | MORPHOLINE OREXIN RECEPTOR ANTAGONISTS | BIAL - Portela & Ca., S.A. (PT) | 2026-02-11 | — | — | EP | disclosed |
| EP-4688155-A1 | MORPHOLINE OREXIN RECEPTOR ANTAGONISTS | Bial-Portela & CA, S.A. (PT) | 2026-02-11 | — | — | EP | disclosed |
| WO-2025023852-A1 | MORPHOLINE OREXIN RECEPTOR ANTAGONISTS | BIAL - PORTELA & CA., S.A. (PT) | 2025-01-30 | — | — | WO | disclosed |
| WO-2025023851-A1 | MORPHOLINE OREXIN RECEPTOR ANTAGONISTS | BIAL - PORTELA & CA., S.A. (PT) | 2025-01-30 | — | — | WO | disclosed |