⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31336954 | 1.00 | — | — | |
| SCHEMBL31336830 | 0.88 | — | — | |
| SCHEMBL31336605 | 0.80 | ALDH1A1 (0.32) | — | |
| SCHEMBL19207158 | 0.73 | DPP4 (0.35) | — | |
| SCHEMBL28646952 | 0.73 | DPP4 (0.35) | — | |
| SCHEMBL31336854 | 0.73 | ALDH1A1 (0.41) | — | |
| SCHEMBL31336642 | 0.70 | USP2 (0.30) | — | |
| SCHEMBL31336850 | 0.69 | HCRTR1 (0.49) | — | |
| SCHEMBL31336882 | 0.69 | HCRTR1 (0.44) | — | |
| SCHEMBL31336719 | 0.68 | NR1H2 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4688154-A1 | MORPHOLINE OREXIN RECEPTOR ANTAGONISTS | BIAL - Portela & Ca., S.A. (PT) | 2026-02-11 | — | — | EP | disclosed |
| WO-2025023851-A1 | MORPHOLINE OREXIN RECEPTOR ANTAGONISTS | BIAL - PORTELA & CA., S.A. (PT) | 2025-01-30 | — | — | WO | disclosed |